Objective: To establish a method for the determination of ginsenoside Rg1

Re

Rb1in Shenqi Particle. Method: The contents of ginsenoside Rg1

Re

Rb1 in Shenqi Particle were determined by HPLC. Result: The resolutions of the determined peaks were fine.The linearity ranges for ginsenoside Rg1

Re

Rb1 were 0.26-4.2 μg(r=0.999 8)

1.0-16.2 μg(r=0.999 9) and 2.5-40.2 μg(r=0.999 9) respectively.The average recoveries were 99.4% with RSD 0.7%

99.6% with RSD 0.7%

99.2% with RSD 0.7%. Conclusion: The quantitative method for the determination was feasible

and beneficial to the quality control of Shenqi Particle.