Long-term Effect of Herbal Drugs of Warming Yang,Reinforcing Qi, Activating Blood on Neuroendocrine in Rats with Heart Failure

ZENG Chui-yi; WANG Zhen-tao

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Long-term Effect of Herbal Drugs of Warming Yang,Reinforcing Qi, Activating Blood on Neuroendocrine in Rats with Heart Failure

更新时间：2024-01-04

- Long-term Effect of Herbal Drugs of Warming Yang,Reinforcing Qi, Activating Blood on Neuroendocrine in Rats with Heart Failure
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 16, Pages: 157-159(2010)
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- Published：2010
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ZENG Chui-yi, WANG Zhen-tao. Long-term Effect of Herbal Drugs of Warming Yang,Reinforcing Qi, Activating Blood on Neuroendocrine in Rats with Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(16): 157-159.
DOI：

ZENG Chui-yi, WANG Zhen-tao. Long-term Effect of Herbal Drugs of Warming Yang,Reinforcing Qi, Activating Blood on Neuroendocrine in Rats with Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(16): 157-159. DOI：

摘要

目的: 观察温阳、益气、活血药物对心力衰竭大鼠神经内分泌的远期疗效。方法: 以结扎冠脉方法复制心肌梗死后心力衰竭大鼠模型

随机分组后分别予附子、人参、丹参浓煎剂、卡托普利

连续3个月

检测血浆中肾素、血管紧张素Ⅱ、醛固酮、心钠肽水平。结果: 附子、人参、丹参均有抑制神经内分泌的作用

以人参作用较强。结论: 温阳、益气、活血药物对心力衰竭大鼠神经内分泌有一定抑制作用。

Abstract

Objective: To study the long-term effect of herbal drugs of warming Yang

reinforcing Qi and activating Blood on neuroendocrine of rats with heart failure. Method: Rat model of heart failure after myocardial infarction was established by ligating the left coronary artery.All rats were randomly divided into groups

fed with aconite

ginseng and radix salviae miltiorrhizae for 3 months

to observe the change of feritin

angiotensin Ⅱ

aldosterone and atrial natriuretic peptide. Result: Aconite

ginseng and radix salviae miltiorrhizae could definitely restrain neuroendocrine

among them ginseng was the strongest. Conclusion: Herbal drugs of warming Yang

reinforcing Qi and activating Blood can restrain neuroendocrine of rats with heart failure.

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Related Institution

Tianjin University of Traditional Chinese Medicine（TCM）

The Second Affiliated Hospital of Tianjin University of TCM

Anhui Province Key Laboratory of Chinese Medicinal Formula， Institute of Integrated Traditional Chinese and Western Medicine，Anhui Academy of Chinese Medicine，Anhui Province Key Laboratory of Chinese Medicinal Formula

Institute of Basic Research in Clinical Medicine，China Academy of Chinese Medical Sciences

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

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