Effect of Shuweitang on Expression of Interstitial Cells of Cajal and Motilin in Functional Dyspepsia Rats
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Effect of Shuweitang on Expression of Interstitial Cells of Cajal and Motilin in Functional Dyspepsia Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 3, Pages: 170-173(2011)
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Published:2011
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HU Shu-juan, WANG Xiao-juan, GUO Xuan, et al. Effect of Shuweitang on Expression of Interstitial Cells of Cajal and Motilin in Functional Dyspepsia Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 170-173.
DOI:
HU Shu-juan, WANG Xiao-juan, GUO Xuan, et al. Effect of Shuweitang on Expression of Interstitial Cells of Cajal and Motilin in Functional Dyspepsia Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(3): 170-173.DOI:
Effect of Shuweitang on Expression of Interstitial Cells of Cajal and Motilin in Functional Dyspepsia Rats
Objective: To observe the effects and mechanism of Shuweitang on expression of interstitial cells of cajal(ICC) and motilin(MTL)in functional dyspepsia(FD) rats. Method: FD model was induced by moderate enraging the rats tail. All rats were divided random1y into 6 groups: control group
model group
high and low dosages of Shuweitang groups
domperidone and Muxiangshunqi groups. Drugs were administrated for 14 days. ICC and MTL were determined by immunohistochemical method.And gastric emptying was observed with phenolsu1fonphthalein. Result: Compared with the control group
gastric emptying and the expression of ICC and MTL in the model groups were obviously decreased (P<0.05). Compared with model group
gastric emptying
MTL and ICC increased significantly in high-dose Shuweitang
Muxiangshunqi and domperidone groups (P<0.05).Low dose of Shuweitang showed no significant differences(P>0.05). Conclusion: High dose of Shuweitang may increase diet and water intake
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Mechanism of Shuweifang Cure Functional Dyspepsia
Clinical Efficacy of Xiangsha Liujunzi Tang Combined with Acupuncture Therapy in Treatment of Syndrome of Deficiency of Spleen Qi and Stomach Qi of Functional Dyspepsia
Effect of Chaihu Shugan San on Serum MOT and ICC-DMP in Rat with Liver Depression Syndrome
Effects of Weiyuanning on Gastrointestinal Motility and Gastrointestinal Hormones in Mice with Functional Dyspepsia
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