Effect of Weishu'an Capsule on Animal Experimental Gastric Ulcer

SHEN Hong; ZHANG Yin-hua; Tian Jia-li; GAO Ying-jie

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Effect of Weishu'an Capsule on Animal Experimental Gastric Ulcer

更新时间：2024-01-04

- Effect of Weishu'an Capsule on Animal Experimental Gastric Ulcer
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 13, Pages: 174-176(2010)
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- Published：2010
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SHEN Hong, ZHANG Yin-hua, Tian Jia-li, et al. Effect of Weishu'an Capsule on Animal Experimental Gastric Ulcer[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(13): 174-176.
DOI：

SHEN Hong, ZHANG Yin-hua, Tian Jia-li, et al. Effect of Weishu'an Capsule on Animal Experimental Gastric Ulcer[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(13): 174-176. DOI：

摘要

目的 :研究胃舒安胶囊对动物实验性胃溃疡的影响。方法 :应用大鼠幽门结扎胃溃疡模型、大鼠醋酸胃溃疡模型、小鼠利血平所致胃溃疡模型，观察胃舒安胶囊对各型溃疡的影响。结果 :胃舒安胶囊对幽门结扎性大鼠胃溃疡有明显防治作用；能显著抑制大鼠的胃液分泌，降低胃总酸度，抑制胃蛋白酶活性；对醋酸性大鼠胃溃疡有促进溃疡愈合的作用；对利血平所致小鼠胃溃疡有抑制作用结论 :胃舒安胶囊对动物实验性胃溃疡具有明显的防治作用。

Abstract

Objective: To research the effect of Weishu’an Capsule on animal experimental gastric ulcer. Method: The effect of Weishu’an Capsule on three kinds of modles of gastric ulcer was observed. The models included the model of pyloroligation gastric ucler in rats

the model of cautery gastric ulcer induced by acetic acid in rats and the model of reserpineinduced gastric ulcer in mice. Result: As to the pyloroligation gastric ucler

Weishu’an Capsule could restrain the secretion of gastric juice

decrease the total gastric acidity

and restrain the activity of pepsin; as to the cautery gastric ulcer

it could promote the ulcer to be healed; as to the reserpineinduced gastric ulcer

it could restrain the ulcer. Conclusion: Weishu’an Capsule has the obvious effect for preventing and treating the animal experimental gastric ulcer.

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Related Institution

The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine

School of Pharmacy， Academy of Chinese Medical Sciences， Henan University of Chinese Medicine

School of Pharmacy of Anhui University of Chinese Medicine，Anhui Province Key Laboratory of Chinese Medicinal Compounds，Synergetic Innovation Center of Anhui Authentic Chinese Medicine， Heifei

Academy of Traditional Chinese Medicine，Henan University of Chinese Medicine

Li Zhenhua Institute of Academic Thought， Henan University of Chinese Medicine

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