Effects of Xingyi Jiangtang Ling on Level of Blood Glucose and Immunologic Function in Diabetic Rats
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Effects of Xingyi Jiangtang Ling on Level of Blood Glucose and Immunologic Function in Diabetic Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 13, Pages: 180-182(2010)
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Published:2010
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DING Wen-jun, JIN Feng, SHEN Ming-xia, et al. Effects of Xingyi Jiangtang Ling on Level of Blood Glucose and Immunologic Function in Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(13): 180-182.
DOI:
DING Wen-jun, JIN Feng, SHEN Ming-xia, et al. Effects of Xingyi Jiangtang Ling on Level of Blood Glucose and Immunologic Function in Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(13): 180-182.DOI:
Effects of Xingyi Jiangtang Ling on Level of Blood Glucose and Immunologic Function in Diabetic Rats
Objective: To explore the effects of Xingyi Jiangtang Ling on blood glucose and immunologic function in diabetic rats. Method: The model of diabetic rat was established by subabdominal injection with streptozotocin 65 mg ·kg-1 and then concomitant hypodemic injection with thyroxine
once a day
from 1th to 7th day. After treated with Xingyi Jiangtang ling for 60 days
the content of TNF-α
IL-4 in the serum of all experimental rats was detected. Result: Compared to normal group
the content of TNF-α in serum of diabetic rats was significantly increased(P<0.01).that of IL-4 was significantly declined. However
the content of TNF-α of treated group was significantly declined
compared with model group(P<0.05). Conclusion: Xingyi Jiangtang Ling can protect immunologic function to β cell in the pancreas by declining TNF-α and increasing of IL-4.It may be one of the mechanisms for antagonizing diabetes.