Objective: To estiblish an HPLC method for ginsenoside Rg1

ginsenoside Re and ginsenoside Rb1 in Naomai Shukang Capsule. Method: An Hypersil-C18 column (4.6 mm×250 mm

5 μm) was used. The mobile phase was composed of acetonitrile (A) and 0.1%phosphoric acid (B) in gradient mode. The detection wavelength was 203 nm. Result: Ginsenoside Rg1

ginsenoside Re and ginsenoside Rb1 showed good linear relationship in the range of 0.210-1.680 mg ·L-1(r=0.999 96)

0.522-4.176 mg ·L-1(r=0.999 98)

1.092-7.644 mg ·L-1(r=0.999 9)respectively. The average recoveries of ginsenoside Rg1

ginsenoside Re and ginsenoside Rb1 were 97.01%(RSD 2.42%

n=5)

97.88%(RSD 1.48%

n=5)

96.19%(RSD 1.67%

n=5) respectively. Conclusion: The method was accurate reliable

and specific

can be used for the quality control of Naomai Shukang Capsule.