Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
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Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 18, Pages: 124-128(2010)
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Published:2010
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LIU Yu-bin, WANG Hui, TANG Xiao-feng, et al. Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 124-128.
DOI:
LIU Yu-bin, WANG Hui, TANG Xiao-feng, et al. Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 124-128.DOI:
Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
Objective: To investigate the utilization of grey relational clustering method in evaluating the treatment of Buzhong Yiqi Tang on rats with Qi-deficiency and fever. Method: SD rats were randomly divided into normal group
Qi-deficiency group
Qi-deficiency and fever group
positive control group (aspirin)
high-dose Buzhong Yiqi Tang group
middle-dose Buzhong Yiqi Tang group and low-dose Buzhong Yiqi Tang group. Swimming strain method and dietary restriction method were utilized to establish the rat model of Qi-deficiency
addition to normal group and Qi-deficiency group
in each group we established the rat model of Qi-deficiency and fever by intraperitoneal injection of LPS. The difference ΔT between rats’ measuring temperature and BBT of each group was then compared. Finally
using gray relational clustering method a comprehensive evaluation of the experimental results was conducted. Result: As for the treatment on rats with Qi-deficiency and fever
aspirin group and high-dose Buzhong Yiqi Tang group were the best
middle-dose Buzhong Yiqi Tang group and low-dose Buzhong Yiqi Tang group ranked behind. Conclusion: Grey relational clustering method can evaluate the effect of Buzhong Yiqi Tang on rats of Qi-deficiency with fever objectively and fairly.
Evaluation of Effect of Buzhong Yiqi Tang on Rats of Qi-deficiency with Fever by Grey Relational Clustering Method
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Related Author
XUE Man-qing2
TANG Xiao-feng1
WANG Hui1
LIU Yu-bin1
Peng-fei KONG
Xian-peng WEI
Xue-gui TANG
Ying ZHANG
Related Institution
School of Traditional Chinese Medicine,Guangdong Pharmaceutical University
School of Nursing,Guangdong Pharmaceutical University
Affiliated Hospital of North Sichuan Medical College
North Sichuan Medical College
Liaoning University of Traditional Chinese Medicine