Optimization of Extracting Technology for Forsythiaside by Orthogonal Test

ZHAO Yan; XUAN Zhen-yu

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Optimization of Extracting Technology for Forsythiaside by Orthogonal Test

更新时间：2024-09-23

- Optimization of Extracting Technology for Forsythiaside by Orthogonal Test
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 11, Pages: 13-15(2010)
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- Published：2010
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ZHAO Yan, XUAN Zhen-yu. Optimization of Extracting Technology for Forsythiaside by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 13-15.
DOI：

ZHAO Yan, XUAN Zhen-yu. Optimization of Extracting Technology for Forsythiaside by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 13-15. DOI：

摘要

目的: 通过正交试验

优选连翘叶中连翘酯苷的最佳提取工艺。方法: 采用正交设计的方法

考察加水量、提取时间、提取次数和提取温度对连翘酯苷得量的影响

优选出最佳提取条件。结果: 各因素的影响依次为: C>A>B>D

提取次数( C )为主要因素

加水量( A )、提取时间( B )、提取温度( D )为次要因素。提取的最佳工艺条件为用16倍的水

60℃温浸法提取3次

每次提取1 h。结论: 优选得到的连翘酯苷的提取工艺简单、稳定、可行。

Abstract

Objective: To establish the optimal extraction technology of forsythiaside by orthogonal test. Method: The amount of water

extraction time

extraction times and extraction temperature were set as index for orthogonal test. Result: The factors were: C > A> B> D . Extraction times ( C ) was as the main factor and the amount of water ( A )

extraction time ( B )

extraction temperature ( D ) as a secondary factor. The optimum conditions for extraction was as follows: 16 times of water

soaking extraction 3 times at 60 ℃

each time extracting for 1 hour. Conclusion: The optimum extraction process for forsythiaside was simple

stable and feasible.

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Related Author

ZHAO Yan1

XUAN Zhen-yu 2

LAN Qun

CHENG Yi

LI Zian

WU Bingyu

WANG Jinyu

LIU Dewen

Related Institution

Shanghai 10th People’s Hospital

Shanghai Youseen Drug Development Corporation

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

上海中医药大学中药现代制剂技术教育部工程研究中心

Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine

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