Progress in Studies on Mechanism of Gardenia Iridoid Glycosides for Cerebral Ischemic Injury

YANG Jun-xuan; ZHANG Hai-yan; ZHAO Cheng-cheng; HUANG Qin-wan; YANG Ming

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Progress in Studies on Mechanism of Gardenia Iridoid Glycosides for Cerebral Ischemic Injury

更新时间：2024-09-23

- Progress in Studies on Mechanism of Gardenia Iridoid Glycosides for Cerebral Ischemic Injury
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 6, Pages: 277-280(2010)
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- Published：2010
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YANG Jun-xuan, ZHANG Hai-yan, ZHAO Cheng-cheng, et al. Progress in Studies on Mechanism of Gardenia Iridoid Glycosides for Cerebral Ischemic Injury[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 277-280.
DOI：

YANG Jun-xuan, ZHANG Hai-yan, ZHAO Cheng-cheng, et al. Progress in Studies on Mechanism of Gardenia Iridoid Glycosides for Cerebral Ischemic Injury[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 277-280. DOI：

摘要

目的: 探讨近几年来栀子环烯醚萜苷治疗脑缺血损伤的作用机制

为栀子环烯醚萜苷类成分的进一步研究和应用提供参考。方法: 查阅国内外相关文献并进行归纳、总结。结果: 环烯醚萜苷类成分是栀子药材的主要化学成分。研究表明

它不仅有明显的保肝利胆、解热、镇静等作用

而且对缺血性脑损伤亦有保护作用。关于栀子环烯醚萜苷类成分对缺血性脑损伤的保护作用研究较多

其作用机制是多方面的。结论: 栀子环烯醚萜苷治疗脑缺血损伤的作用机制有待进一步研究。

Abstract

Objective: To review the progress in studies on mechanism of gardenia iridoid glycosides for treatment of cerebral ischemic injury

so as to provide more information on gardenia iridoid glycosides for further research and application. Method: The literatures published home and abroad in recent years were consulted and summarized. Result: Gardenia iridoid glycosides are the main chemical components in Fructus Gardeniae. Modern studies show that gardenia iridoid glycosides not only have protective effects in liver gallbladder

antipyretic

sedative and other effects

but also have protective effects against ischemic brain injury. Currently there are more studies about gardenia iridoid glycosides against ischemic brain injury

and the mechanism is multifaceted. Conclusion: More studies are needed on the mechanism of gardenia iridoid glycosides for treatment of cerebral ischemic injury.

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Related Author

YANG Jun-xuan1

ZHANG Hai-yan2

ZHAO Cheng-cheng1

HUANG Qin-wan1

YANG Ming1

DOU Xin

PAN Haidi

HE Changhui

Related Institution

College of Pharmacy,Chengdu University of Traditional Chinese Medicine

Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Traditional Chinese Medicine

The First Clinical Medical College，Shandong University of Traditional Chinese Medicine（TCM）

College of TCM，Shandong University of TCM

The Affiliated Hospital of Shandong University of TCM

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