Study on Changes of Chemical Constituents in Tripterygium wilfordii during Process of Fermenting
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Study on Changes of Chemical Constituents in Tripterygium wilfordii during Process of Fermenting
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 10, Pages: 59-62(2010)
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Published:2010
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ZHANG Pu-zhao, YANG Li-juan, HOU Zhi-fan, et al. Study on Changes of Chemical Constituents in Tripterygium wilfordii during Process of Fermenting[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(10): 59-62.
DOI:
ZHANG Pu-zhao, YANG Li-juan, HOU Zhi-fan, et al. Study on Changes of Chemical Constituents in Tripterygium wilfordii during Process of Fermenting[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(10): 59-62.DOI:
Study on Changes of Chemical Constituents in Tripterygium wilfordii during Process of Fermenting
The content of total diterpenoids and total alkaloids were determined by UV spectrophotometry and triptolide and two main alkaloids contents were assayed by HPLC in order to study on the changes of chemical constituents in Tripterygium wilfordii during the process of fermenting.The results showed that after materials being fermented for 90 days
the content of total diterpene and total alkaloids decreased by 46% and 13%
respectively
at the same time
triptolide content decreased by 89.4%
while the contents of wilforgine and wilforine decreased by little.It were concluded that fungi have large influence on the content of total diterpene in T. wilfordii F and less influence on total alkaloid during bi-directional fermentation in this paper.
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