Study on Quality Standards for Shenhua Capsules

WANG Fang; LI Xue-qing; LIU Yu-lin; LIU Zi-dong

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Study on Quality Standards for Shenhua Capsules

更新时间：2024-09-23

- Study on Quality Standards for Shenhua Capsules
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 2, Pages: 39-41(2010)
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- Published：2010
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WANG Fang, LI Xue-qing, LIU Yu-lin, et al. Study on Quality Standards for Shenhua Capsules[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 39-41.
DOI：

WANG Fang, LI Xue-qing, LIU Yu-lin, et al. Study on Quality Standards for Shenhua Capsules[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 39-41. DOI：

摘要

目的: 建立参花胶囊的质量标准。方法: 采用TLC法对本方中的川芎、丹参进行定性鉴别;采用HPLC法对处方中主要成分丹参酮ⅡA进行含量测定。结果: 薄层色谱斑点清晰

阴性对照无干扰。含量测定丹参酮ⅡA在0.03~0.64 μg范围呈良好的线性关系

r=0.999 8

平均回收率99.57%

RSD为0.99%(n=6)。结论: 所建立的方法可靠准确地进行定性、定量检测

可用于该制剂的质量控制。

Abstract

Objective: To establish the quality standard for Shenhua capsules. Methods: The TLC method was used to identify Szechwan Lovage Rhizome and Danshen Root and the HPLC method was used to determine tanshinone ⅡA in the preparation. Results: TLC spots clear and specific.A good linear relationship between peak areas and concentrations of tanshinoneⅡA was found at the range of 0.03~0.64 μg with a correlation coefficient of r=0.999 8. The average recovery of tanshinoneⅡA was 99.57% and RSD was 0.99%(n=6). Conclusions: The method is reliable

accurate and specific.It can be used for the quality control of Shenhua Capsules.

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Related Author

WANG Fang~1

LI Xue-qing~2

LIU Yu-lin~

刘子冬

ZHANG Xiao-yan

YANG Xiu-ping

WANG Jian-ming

DENG Mao1

Related Institution

1*),LIU Zi-dong~1

第四军医大学西京医院药剂科

Pharmaceutical College of Henan University of Traditional Chinese Medicine

Pharmaceutical College,Jilin University

Jilin Agricultural University

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