Correlations Between Amino Acid Contents and Cold or Hot Nature of Traditional Chinese Material Medica

FENG Shuai; LI Feng; ZHOU Zheng-li; LI Jian

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Correlations Between Amino Acid Contents and Cold or Hot Nature of Traditional Chinese Material Medica

更新时间：2024-09-23

- Correlations Between Amino Acid Contents and Cold or Hot Nature of Traditional Chinese Material Medica
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 11, Pages: 91-95(2010)
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- Published：2010
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FENG Shuai, LI Feng, ZHOU Zheng-li, et al. Correlations Between Amino Acid Contents and Cold or Hot Nature of Traditional Chinese Material Medica[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 91-95.
DOI：

FENG Shuai, LI Feng, ZHOU Zheng-li, et al. Correlations Between Amino Acid Contents and Cold or Hot Nature of Traditional Chinese Material Medica[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 91-95. DOI：

摘要

目的 :初步探讨中药寒热药性与18种氨基酸含量的相关性

建立寒热药性的Fisher判别函数。方法 :采用反相高效液相色谱法、紫外分光光度法测定了30味中药中的18种氨基酸含量。以18种氨基酸含量为指标

利用Fisher方法建立判别函数

研究中药药性与氨基酸含量的相关性。结果 :热性中药的18种氨基酸平均含量是寒性中药的1.32倍

建立寒热药性的Fisher判别函数

组内回代一致率为90%。结论 :Fisher判别函数对30种中药的寒热药性实现了较为准确的判别。18种氨基酸含量与中药寒热药性具有相关性。

Abstract

Objective: The aim of the paper was to study the relationship between 18 kinds of amino acid contents and cold or hot nature of traditional Chinese material medica and establish discriminant function. Method: Extracting eighteen kinds of amino acid from thirty kinds of TCM. Seventeen kinds of amino acid contents were determined by high performance liquid chromatography(HPLC) with precolumn phenylisothiocyanate derivatization spectrophotometry. Tryptophan were determined by ultraviolet spectrophotometry. The Fisher discriminant analysis was used to analyze the relationship between amino acid and cold or hot nature of traditional Chinese material medica. Result: Form the determinantion of 18 kinds of amino acid contents

it showed that the average amino acid contents of the heat is 1.32 times than the one of the cold

the correct rate is ninety percent analyzed by Fisher discriminant analysis. Conclusion: Form the results of fisher discriminant of 18 variables

it revealed that there are many differences between the cold and hot property in 18 kinds of amino acid contents. Based on the analysis of the determined data

a discrimination function was established and it could distinguish cold and hot property of Chinese herbs.

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Related Author

LI Jian

ZHOU Zheng-li

LI Feng

FENG Shuai

Zhuan-xia MA

Zhi-rong GU

Bin GE

Mei QI

Related Institution

College of Pharmacology of Shandong University of Traditional Chinese Medicine

Gansu Provincial Hospital

College of Pharmacy, Gansu University of Chinese Medicine

Gansu Province Key Laboratory of Pharmacology and Toxicology of Traditional Chinese Medicine

广州中医药大学,广州中医药大学,广州中医药大学,广州中医药大学,广州中医药大学

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