Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice
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Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 9, Pages: 128-130(2010)
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Published:2010
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SHI Yuan, LI Xia, ZHAO Jiang-he, et al. Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 128-130.
DOI:
SHI Yuan, LI Xia, ZHAO Jiang-he, et al. Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 128-130.DOI:
Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice
各给药组对小鼠肠运动的促进作用均显著高于空白组( P <0. 01)。 结论 :HYYPSCS显著促进胃肠蠕动且对乙醇致小鼠胃黏膜损伤具有保护作用
其作用机制可能与其抗氧化作用有关。
Abstract
Objective: To investigate the effect of Concentrated Mineral Water and Chinese Hebal Compound (HYYPSCS) on gastrointestinal function in mice. Method: HYYPSCS (7700
3850 and 1925 mg·kg-1) was ig administrated once a day for 5 days. Acute gastric lesion was induced by ethanol in mice. The ulcer index
ulcer inhibition rate
SOD
MDA and the effect of HYYPSCS on intestinal activities was assessed. Result: Compared with ethanol group
HYYPSCS significantly reduced the ulcer index ( P <0.01)
MDA activity ( P <0.01) and SOD activity was significantly increased ( P <0.05). Compared with Normal group
HYYPSCS can significantly excited intestinal propulsive function ( P <0.01). Conclusion: HYYPSCS can excite gastrointestinal peristalsis and has protective effect on the gastric lesion induced by ethanol in mice.
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XIANG Xi
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ZHANG Yang
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XU Erping
Related Institution
The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine
School of Pharmacy, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine
School of Pharmacy of Anhui University of Chinese Medicine,Anhui Province Key Laboratory of Chinese Medicinal Compounds,Synergetic Innovation Center of Anhui Authentic Chinese Medicine, Heifei
Academy of Traditional Chinese Medicine,Henan University of Chinese Medicine
State Key Laboratory Breeding Base of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences