Studies on extraction process of cichoric acid in Echinacea purpurea
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Studies on extraction process of cichoric acid in Echinacea purpurea
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 4, Pages: 1-4(2010)
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Published:2010
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ZHONG Ying-jie, LI Liang, XU Fu-liang. Studies on extraction process of cichoric acid in Echinacea purpurea[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 1-4.
DOI:
ZHONG Ying-jie, LI Liang, XU Fu-liang. Studies on extraction process of cichoric acid in Echinacea purpurea[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 1-4.DOI:
Studies on extraction process of cichoric acid in Echinacea purpurea
Objective: To establish the optimal extraction technology and to determine the quantity of cichoric acid from Echinacea purpurea. Method: Nine experiments were carried out through L9(34) orthogonal design. The contents of cichoric acid were determined by HPLC. Result: The best extraction condition obtained was 12 times amount 60% alcohol and extracted for 3 times
1.5 hours each time. Cichoric acid was linear within the range of 0.011~1.100 mg
r =0.999 8. The average recovery is 99.51%(RSD=1.01%
n=6). Conclusion : This optimal technology is stable and workable
can be used in industrial production. The determination method is suitable for quality control.
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Related Author
ZHONG Ying-jie
LI Liang
XU Fu-liang
WANG Kun
ZHANG Zhen-ling
JIA Xiu-mei
HAN Zhong-yao
ZHOU Fu-jun
Related Institution
Qingdao Kangdien Pharmaceutical Co.,Ltd
Tianjin University of Traditional Chinese Medicine
Tianjin Institute of Pharmaceutical Research
Key Laboratory of Active Ingredients in Traditional Chinese Medicine(TCM) Co-constructed by Jilin Province and Ministry of Education, Changchun University of Chinese Medicine