Objective: To study the eugenol contents of micropowder and coarse powder of Flos Caryophylli and the effects on intestinal motility in mice. Method: HPLC was used to determine the contents of eugenol in ultramicro-powder and coarse powder of Flos caryophylli. Charcoal powder propelling test of intestine was used to observe the effects on intestinal mobility in mice for coarse powder and different doses of micropowder. Result: The contents of eugenol were the same in the two kinds of power

Flos caryophylli can obviously inhibit intestinal motility. The effects were the same when the dose of micropowder was 25 percent of that of coarse powder. There was a dose-effect relationship in inhibiting intestinal motility for micropowder. Conclusion: The application of super-crash in Flos caryophylli is significant. The dose of micropowder can be reduced correctly for saving medical material when it is used in clinic.