Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats
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Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 2, Pages: 78-80(2010)
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Published:2010
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REN Jun-guo, MA Xiao-bin, LIN Cheng-ren, et al. Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 78-80.
DOI:
REN Jun-guo, MA Xiao-bin, LIN Cheng-ren, et al. Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(2): 78-80.DOI:
Protective Effect of Jiawei Shengmaisan Against Acute Myocardial Ischemia/Reperfusion Injury in Rats
Objective: To investigate protective effect of Jiawei Shengmaisan against acute myocardial ischemia/reperfusion injury in rats. Methods: The acute myocardial ischemia/reperfusion injury in rats was induced by ligating the anterior descending coronary artery in SD rats and administered different dosage jiawei shengmaisan decotion into duodenum
myocardial infarction degree(MID) was calculated by detcting myocardial infarction area with nitroblue tetrazolium(NBT) assay
SOD activities and MDA、NO contents were detected with biochemical assay. Results: Jiawei shengmaisan can significantly decreased MID and MDA contents in serum
increased SOD activities and NO contents in serum. Conclusions: The results showed that Jiawei shengmaisan has protective effect against acute myocardial ischemia/reperfusion injury in rats
which may be relate to its antioxygen action and NO.
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Related Author
LIU Jian-xun
LI Jun-mei
WANG Min
LI Hong-hai
WANG Yang-hui
REN Jun-guo
MA Xiao-bin
LIN Cheng-ren
Related Institution
Center for Experimental Research,Xiyuan Hospital,China Academy of Chinese Medical Sciences
Hebei Industrial Technology Institute for Traditional Chinese Medicine Preparation