Objective: To establish a high performance liquid chromatographic method to determine the dissolution of β-asarone in Shenqiyinao Capsules. Method: The column was Lichrospher(r)100 RP-18e (4.6 mm×250 mm

5 μm). The mobile phase composed of methanol-0.1% glacial acetic acid solution (60 ∶40) and the temperature of column was 35 ℃. The flow rate was 1.0 mL ·min-1 and the detective wavelength was at 257 nm

external method. The dissolution of the β-asarone was determined by basket stirring technique with 0.5％ sodium dodecyl sulfate 500 mL at a speed of 100 r ·min-1. Result: The linear range of β-asarone was 0.007~0.352 μg. The dissolution of β-asarone was above 70% at 30 minutes. Conclusion: The method is sensitive

accurate and suitable for the quality control of Shenqiyinao Capsules.