Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises

LI Yong-feng; HAN Yong; GUO Yong-li; WANG Chuan-jun; LI Ye

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Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises

更新时间：2024-09-23

- Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 16, Issue 6, Pages: 224-227(2010)
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- Published：2010
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LI Yong-feng, HAN Yong, GUO Yong-li, et al. Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 224-227.
DOI：

LI Yong-feng, HAN Yong, GUO Yong-li, et al. Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 224-227. DOI：

摘要

目的 :探讨黄芪注射液对两种力竭运动大鼠血清肌酸激酶(CK)及其同工酶的影响

为减轻运动性肌肉损伤寻找有效的方法。方法 :将50只大鼠随机均分为5组

各10只:安静对照组、一次性力竭运动组、多次力竭运动组、服药+一次性力竭运动组、服药+多次力竭运动组。经过4周的实验后

测血清CK及其同工酶的含量。结果: 一次力竭和多次力竭大鼠血清CK及其同工酶活性显著增高(P<0.01)

黄芪注射液对一次力竭和多次力竭大鼠血清CK及其同工酶活性有降低作用(P<0.01)。结论: 黄芪注射液对减轻2种力竭运动引起的肌肉损伤均有很好的作用。

Abstract

Objective: In order to search potent means for exercise-induced muscle damage

effect of Radix Astragali injection on serum creatine kinase(CK) and isoenzyme of creatine kinase(CK-MM) level in rats after two kind of Exhausting Exercises was observed. Method: 50 Wister Rats were randomLy divided into 5 group: normal control group(n=10)

once exhausting exercise group(n=10)

multiple exhausting exercises group(n=10)

Radix Astragali injection filled the stomach and once exhausting exercise group(n=10)

Radix Astragali injection filled the stomach and multiple exhausting exercises group (n=10). After 4 weeks test

serum CK and CK-MM were tested. Result: Afer exhausting exercise

CK and CK-MM in blood serum as well as were higher than that in normal control group(P<0.01).the change was prevented by Radix Astragali injection(P<0.01). Conclusion: Radix Astragali injection may help reduce exercise-induced muscle damage afer two kind of exhausting exercises.

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Related Author

HAN Yong

GUO Yong-li

WANG Chuan-jun

LI Ye

LI Yong-feng

ZHAO Qiang3

LIU Hai-peng2

WANG Qin-mao2

Related Institution

Shandong Sports University

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