Study on Flocculation Procedure with Chitosan for Xiang A-2 Granules

JIANG Min1; 2; XIA Xin-hua1

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Study on Flocculation Procedure with Chitosan for Xiang A-2 Granules

更新时间：2024-01-04

- Study on Flocculation Procedure with Chitosan for Xiang A-2 Granules
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 15, Issue 6, Pages: 33-36(2009)
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- Published：2009
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JIANG Min1, 2, XIA Xin-hua1. Study on Flocculation Procedure with Chitosan for Xiang A-2 Granules[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(6): 33-36.
DOI：

JIANG Min1, 2, XIA Xin-hua1. Study on Flocculation Procedure with Chitosan for Xiang A-2 Granules[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(6): 33-36. DOI：

摘要

目的:探索壳聚糖用于湘A-2号颗粒的最佳絮凝澄清工艺条件。方法:在对壳聚糖加入量、药液浓度、pH值、温度、搅拌速度等进行单因素考察后

采用正交试验法对药液浓度、壳聚糖加入量、及药液pH值进行优化。结果:湘A-2号颗粒的絮凝工艺的优化条件为:壳聚糖加入量0.6mL·g-1

药液浓度为1∶4

药液pH值为7

温度60℃

搅拌速度为200r·min-1

搅拌时间为10min。结论:壳聚糖絮凝澄清工艺可用于湘A-2号颗粒的纯化。

Abstract

Objective:To study the flocculation process with chitosan for Xiang A-2 Granules. Methods On the basis of the one-factor investigation such as the amount of chitosan

the concentration and pH of the extracting solution

temperature and stirring etc

the experiments for the further optimization of flocculation process conditions were arranged with orthogonal design.Results:The optimal flocculation process conditions were as follows. The adding amount of chitosan was 0.6 mL·g-1

the extract solution and medicinal materials were in the ratio of one to four 1∶4

the PH of the solution was 7

the flocculation temperature was 60 ℃

the stirring speed was 200 r·min-1 and the stirring time was 10 minutes. Conclusion:The flocculation process with chitosan can be used for the purification of Xiang A-2 Granules.

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