Study on Refining Technology of Wuzhuyu-tang by Macroporous Resin
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Study on Refining Technology of Wuzhuyu-tang by Macroporous Resin
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 5, Pages: 1-7(2010)
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Published:2010
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WANG Ya-xin, GONG Mu-xin, WANG Zhi-min, et al. Study on Refining Technology of Wuzhuyu-tang by Macroporous Resin[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 1-7.
DOI:
WANG Ya-xin, GONG Mu-xin, WANG Zhi-min, et al. Study on Refining Technology of Wuzhuyu-tang by Macroporous Resin[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 1-7.DOI:
Study on Refining Technology of Wuzhuyu-tang by Macroporous Resin
Objective: To set up a proper technology of refining of the aqueous extract of Wuzhuyu-tang. Method: 7 kind components which had been improved to be absorbable pharmacological ingredients were chosen as index for refining. The static adsorption
dynamic adsorption and leakage curve experiments were done to choose a proper resin. By means of single-factor experiment and orthogonal experiment
the optimum refining conditions were found
such as adsorption time
proportion of sample weight and resin volume
proportion of diameter and height
concentration of decoction and eluent
flow rate
eluent volume and so on. Result: The AB-8 resin had the best separating efficiency when the content in the aqueous extract was 0.33g per 1mL equivalent to raw material
the ratio of dia-height was 1:4
and the volume of 60% ethanol as eluant 8BV with desorption-power 0.1BV/min. Conclusion: The content of 7 kind components were over 70% after refining
5 of them were over 90%. It is concluded that the optimized extracting and refining technology is reasonable and feasible.
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Related Author
WANG Ya-xin1
GONG Mu-xin1
WANG Zhi-min2
ZHANG Qi-wei2
Bing-bing ZHANG
Ze-min OU
Lin YAN
Yao ZHANG
Related Institution
Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences
College of Pharmacy of Chinese Medicine,Capital University of Medical Sciences
School of Pharmacy,Tianjin University of Traditional Chinese Medicine
School of Pharmacy, Jiangxi University of Chinese Medicine
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences