Optimization the Water Extracting Technology for Pingzhi Capsule and determination of Total Anthraquinones in it

YANG Hui; HUANG Yi-qi; LUO You-hua

您当前的位置：

首页 >

文章列表页 >

Optimization the Water Extracting Technology for Pingzhi Capsule and determination of Total Anthraquinones in it

更新时间：2024-01-04

- Optimization the Water Extracting Technology for Pingzhi Capsule and determination of Total Anthraquinones in it
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 15, Issue 12, Pages: 48-51(2009)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2009
- 稿件说明：
移动端阅览
YANG Hui, HUANG Yi-qi, LUO You-hua. Optimization the Water Extracting Technology for Pingzhi Capsule and determination of Total Anthraquinones in it[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(12): 48-51.
DOI：

YANG Hui, HUANG Yi-qi, LUO You-hua. Optimization the Water Extracting Technology for Pingzhi Capsule and determination of Total Anthraquinones in it[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(12): 48-51. DOI：

摘要

目的:优选平脂胶囊最佳水提工艺

建立其总蒽醌含量的紫外分光光度测定方法。方法:以总蒽醌含量和干膏得率为考察指标

采用L9(34)正交实验方法优选平脂胶囊水提工艺。利用蒽醌类化合物遇碱显红色或紫红色反应

524nm波长处直接测定试样的吸收度。结果:最佳水提工艺:10倍量水

提取3次

每次1.5h。对照品1

8-二羟基蒽醌浓度在3.2～16μg·mL-1范围内吸收度与浓度呈良好的线性关系

r=0.9996

样品平均回收率99.17%

RSD为2.01%。结论:该工艺稳定、可行

紫外分光光度法灵敏、快速、准确、成本低

适用于平脂胶囊中总蒽醌的测定。

Abstract

Objective: To optimize the water extracting technology for Pingzhi capsule and establish a ultraviolet spectrophotometric method for the determination of total anthraquinones in Pingzhi capsule.Method: The extracting technology of Pingzhi Capsule was optimized by orthogonal experiment with total anthraquinones and the yield of extrac as the markers.Color reaction(Borntragers reaction) occurs sensitively when anthraquinones are in the albaline solution

producing stably red or purple-red color.The absorption value of the colored sample solution was measured at 524 nm.Results: The optimum extracting condition was adding 10 times water and extracting 1.5h/time for 3 times.The calibration curve indicated that the absorptivity was linearly correlated with the concentration of 1

8-dihydroxy anthraquinone in the range of 3.2～16 μg·mL-1(r=0.999 6). The average recovery of 1

8-dihydroxy anthraquinone was 99.17% and RSD was 2.01%.Conclusion: The technology is stable and easy to be operated.The method of direct ultraviolet spectrophotometry is accurate

sensitive

quick and cost effective and it can be used to determine total anthraquinones in Pingzhi capsule.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Experimental Study of Extracting Technology Optimization withOrthogonal Design for Tuibai Decoction

Investigation of Metabolic Stability of Phase Ⅰ and Ⅱ Sulfation of Lucidin in Liver Microsomes and Liver S9 from Different Species

Analysis on Chemical Constituents in Xiao Chengqitang by UPLC-Q-Orbitrap-MS

Analysis of Chemical Composition in Sancao Baogan Decoction Based on UPLC-ESI-HRMSⁿ

Anti-cancer Effect of Anthraquinones in Polygoni Multiflori Radix

Related Author

SHENG Guo-rong

Yuexin MA

Ying ZHANG

Jing YANG

Youlong FENG

Qing HUANG

Ling CAO

Si-ni LUO

Related Institution

Jiangsu Institute for Food and Drug Control

School of Pharmacy，Nanjing University of Chinese Medicine

School of the Fifth Clinical Medicine，Guangzhou University of Chinese Medicine

Guangdong Efong Pharmaceutical Co. Ltd.，Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granule

College of Pharmacy, College of Life Science and Technology, Southwest Minzu University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰