Study on Alcohol Precipitation Techniques for Eczema spray

SUN Meng-jin1; HE Qun1; ZHAO Bi-qing1; YANG Zhi-bo2; CHEN Ben-chao1

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Study on Alcohol Precipitation Techniques for Eczema spray

更新时间：2024-01-04

- Study on Alcohol Precipitation Techniques for Eczema spray
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 15, Issue 12, Pages: 45-47(2009)
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- Published：2009
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SUN Meng-jin1, HE Qun1, ZHAO Bi-qing1, et al. Study on Alcohol Precipitation Techniques for Eczema spray[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(12): 45-47.
DOI：

SUN Meng-jin1, HE Qun1, ZHAO Bi-qing1, et al. Study on Alcohol Precipitation Techniques for Eczema spray[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(12): 45-47. DOI：

摘要

目的:研究湿疹喷雾剂水提醇沉纯化工艺最优条件。方法:以苦参碱含量为评价指标

采用正交设计试验法对湿疹喷雾剂的水提液醇沉工艺进行优化。结果:徐长卿、苦参醇沉最优工艺参数为:水提取液浓缩至药材∶溶剂(g∶mL)为1∶0.57

含醇量70%

醇沉时间12h。结论:该醇沉纯化工艺合理、可行

可为湿疹喷雾剂工业化生产中药材前处理提供依据。

Abstract

Objective: To study the optimal conditions of the water extracting and alcohol precipitation techniques for Eczema Spray.Methods: The content of Matrine were used as the assessment markers.The water extracting and alcohol precipitation techniques for Eczema Spray was optimized with orthogonal design experiment.Results: The optimal technological parameters of the alcohol precipitation techniques for Cynanchum paniculatum and Radix sophorae flavescentis were as follows: the ratio between medicinal materials and solvent is 1 to 0.57

the percentage of alcohol is 70%

and the time of alcohol precipitation is 12 hours.Conclusion: The optimized extract conditions are reasonable and feasible

and it provides foundation for pre-preparation of crude material of eczema spray's industrialize production.

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Related Author

CHEN Linzhen

ZHANG Xue

CHEN Qi

YU Xue

DAI Shengyun

MA Zhiqiang

ZHAO Chongjun

SI Qin

Related Institution

Beijing Key Laboratory of Traditional Chinese Medicine（TCM） Quality Evaluation， Beijing University of Chinese Medicine

School of TCM， Beijing University of Chinese Medicine

National Institutes for Food and Drug Control

National Engineering Laboratory for Quality Control Technology of Chinese Materia Medica， Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

Medicinal College， Guangxi University

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