Effect of Xinshi Injection on Cerebral Blood Flow,Cerebrovascular Resistance and Antioxidant Activity in Brain Tissue in Dogs
|更新时间:2024-01-04
|
Effect of Xinshi Injection on Cerebral Blood Flow,Cerebrovascular Resistance and Antioxidant Activity in Brain Tissue in Dogs
Chinese Journal of Experimental Traditional Medical FormulaeVol. 15, Issue 6, Pages: 56-58(2009)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2009
稿件说明:
移动端阅览
KAN Hong-wei1, 4, WEI An-xiang2, et al. Effect of Xinshi Injection on Cerebral Blood Flow,Cerebrovascular Resistance and Antioxidant Activity in Brain Tissue in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(6): 56-58.
DOI:
KAN Hong-wei1, 4, WEI An-xiang2, et al. Effect of Xinshi Injection on Cerebral Blood Flow,Cerebrovascular Resistance and Antioxidant Activity in Brain Tissue in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(6): 56-58.DOI:
Effect of Xinshi Injection on Cerebral Blood Flow,Cerebrovascular Resistance and Antioxidant Activity in Brain Tissue in Dogs
Objective:To study the effect of Xinshi Injection (XSI) on cerebral blood flow (CBF)
cerebrovascular resistance (CVR)
concentration of SOD
MDA and NO of brain tissue in anesthetized dogs. Methods: Healthy dogs were divided into normal sodium (NS) control group
Danshen injection group and XSI high dose group (4 g·kg-1)
middle dose group(2 g·kg-1) and low dose group (1 g·kg-1). After anesthetized by 3% carbrital
the femoral vein of left lower extremity (LLE) was separated to iv XSI; the left common carotid artery was separated to measure the blood flow of internal carotid artery; the femoral artery of LLE was separated to determine mean arterial blood pressure
then the CBF and CVR were calculated. The concentration of SOD
MDA and NO were measured by kits respectively. Results: XSI increased the blood flow in brain tissue and decreased CVR significantly. It also increased concentration of SOD and decreased concentration of MDA and NO in the brain tissue. Conclusion: XSI can improve blood flow of dog's brain and dilate cerebral vessels of dog.
Antioxidant and Anti-tumor Effect and Mechanisms of Andrographis paniculata Polysaccharide on Human Cervical Cancer HeLa Cells
Structural Characteristics and Antioxidant Activity Analysis of Polysaccharides from Pinelliae Rhizoma and Its Processed Products Before and After Hydrolysis (Enzymolysis) by Sugar Spectrum
Research Progress in Extraction Technology, Structural Characteristics and Pharmacological Activities of Hippophae rhamnoides Polysaccharides
Role of Flavonoids in Traditional Chinese Medicine to Improve Cerebral Ischaemia-reperfusion Injury and Its Mechanism: A Review
Analysis on Advantages of New Integration Processing Method in Producing Area of Polygoni Multiflori Radix Praeparata
Related Author
HUANG Lijin
LI Zilin
YANG Ziyan
WANG Han
CHEN Guiyuan
HU Meibian
GAO Kuixu
WANG Yao
Related Institution
Provincial Key Laboratory of Entomology Biopharmaceutical R&D,Dali
Basic Medicine School, Dali University, Dali
School of Traditional Chinese Medicine(TCM) and Food Engineering,Shanxi Provincial Key Laboratory of TCM Processing,Shanxi University of Chinese Medicine
School of Pharmacy,Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province,Chengdu University
Medical School, Lijiang Culture and Tourism College