Purification of Salvianolic Acid by Macroporous Resins
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Purification of Salvianolic Acid by Macroporous Resins
Chinese Journal of Experimental Traditional Medical FormulaeVol. 16, Issue 6, Pages: 14-16(2010)
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Published:2010
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LUO Duo-sheng, He Wei, GUO Jiao. Purification of Salvianolic Acid by Macroporous Resins[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 14-16.
DOI:
LUO Duo-sheng, He Wei, GUO Jiao. Purification of Salvianolic Acid by Macroporous Resins[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 14-16.DOI:
Purification of Salvianolic Acid by Macroporous Resins
Objective: To study the optimum conditions for the purification of salvianolic acid by macroporous resins. Method: The macroporous resin was selected and the purification process was evaluated by measuring the content of salvianolic acid B. Result: The HPD-300 maoroporous resin was the most effective one among the resins. The optimum conditions were screened
the adsorption capacity of HPD-300 macroporous resin was 172.4 mg/g
pH was 3.5; and the volume of 70% ethanol as eluent was 3 BV. By this method
the yield of salvianolic acid B was 88.11%; and the purity was 72.80%. Conclusion: The method is effective for purification of salvianolic acid.
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Related Author
HE Wei2
GUO Jiao1
LUO Duo-sheng1
YAN Yan-fang
ZHANG Zhuang
NIE Bo
LI Jia-yan
阿依先木·
Related Institution
Key Unit of Modulating Liver to Treat Hyperlipemia SATCM
Institute of Medica of Guangdong Pharmaceutical University
School of Chinese Pharmacy,Beijing University of Chinese Medicine
Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine,Key Laboratory of Chinese Internal Medicine of Education and Key Laboratory of Beijing City,Beijing University of Chinese Medicine