Effects of Xiaoyanlidanpian on Experimental Hepatitis and Acute Inflammation
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Effects of Xiaoyanlidanpian on Experimental Hepatitis and Acute Inflammation
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 11, Pages: 45-48(2008)
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Published:2008
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YIN Xiao-ping1, KURIHARA Hiroshi1, BAO Li2, et al. Effects of Xiaoyanlidanpian on Experimental Hepatitis and Acute Inflammation[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(11): 45-48.
DOI:
YIN Xiao-ping1, KURIHARA Hiroshi1, BAO Li2, et al. Effects of Xiaoyanlidanpian on Experimental Hepatitis and Acute Inflammation[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(11): 45-48.DOI:
Effects of Xiaoyanlidanpian on Experimental Hepatitis and Acute Inflammation
Objective:To investigate the effects of Xiaoyanlidanpian(XLP) on mice model of experimental hepatitis and acute inflammation.Methods:The experimental hepatitis model was established by injection of Propionibacterium acnes and lipopolysaccharide(P.acnes-LPS) via lateral tail vein.Hepatic function was evaluated by assessing Alanine aminotransferase level(ALT) in plasma.The effect of Xiaoyanlidanpian on allergic contact dermatitis (ACD) induced by DNFB was studied in mice to observe its effect on delayed-type-hypersensitivity(DTH).Croton oil and Carrageenan were used as well to observe its effect on acute inflammation.Results: Compared to the model group
Xiaoyanlidanpian can inhibite the activities of ALT in mice plasma.Meanwhile
Xiaoyanlidanpian could ameliorate the ear swelling in ACD model and acute inflammatory model induced by croton oil.It also reduced the thickness of the mice hind paw induced by carrageenan as well.Conclusion:Xiaoyanlidanpian exerted potential effects on experimental hepatitis.Xiaoyanlidanpian also show partial effect on acute inflammation.
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