Research on the Influence of Various Compatibility on Fingerprint of Yupingfeng Decoction by HPLC

YIN Xue1; HUANG Yue-chun2; WEI Gang1

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Research on the Influence of Various Compatibility on Fingerprint of Yupingfeng Decoction by HPLC

更新时间：2024-01-04

- Research on the Influence of Various Compatibility on Fingerprint of Yupingfeng Decoction by HPLC
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 15, Issue 3, Pages: 1-3(2009)
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- Published：2009
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YIN Xue1, HUANG Yue-chun2, WEI Gang1. Research on the Influence of Various Compatibility on Fingerprint of Yupingfeng Decoction by HPLC[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(3): 1-3.
DOI：

YIN Xue1, HUANG Yue-chun2, WEI Gang1. Research on the Influence of Various Compatibility on Fingerprint of Yupingfeng Decoction by HPLC[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(3): 1-3. DOI：

摘要

目的:研究不同配伍对玉屏风煎剂中主要特征指纹峰的影响。方法:采用HPLC法分析单煎及不同配伍煎剂样品

色谱柱为HypersilODS;流动相为乙腈-水(梯度洗脱);检测波长为220nm;流速为1mL·min-1;柱温为30℃。结果:全方煎剂的特征指纹峰基本为各药味特征峰的加和

未产生明显的新特征峰

不同配伍对玉屏风煎剂中主要特征峰的峰面积有不同影响

但总体影响不大。玉屏风汤剂中共标示出11个共有峰

分别以黄芪、防风药材单煎为基准

计算配伍后的均值相似度

结果表明不同配伍玉屏风汤剂与黄芪单煎的主要特征成分的相似度在0.97以上;与防风单煎的主要特征成分相似度在0.98以上

说明配伍对黄芪、防风特征锋的影响不明显。结论:本研究为玉屏风煎剂配伍规律及物质基础研究提供了一定参考。

Abstract

Objective: To study the influence of various compatibilities on fingerprint in the decoctions.Methods: HPLC with Hypersil ODS was used

acetonitrile-water(gradient elution) as a mobile phase and detection wavelength at 220 nm

flow rate was 1 mL·min-1

and column temperature was 30 ℃.Results: The characteristic peaks were the summation.Various influence on characteristic peaks were found in various compatibilities of the decoctions

but there was no new characteristic peaks.11 common peaks were separated in Yupingfeng Decoction.There was not obviously influence about correlation of various compatibilities. Conclusion:The study provides a reference for the rules of the compatibility and material base of Yupingfeng Decoction.

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Related Institution

Henan College of Traditional Chinese Medicine

ZHEJIANG A & F UNIVERSITY

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College of Pharmacy,Yanbian University,Yanji

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