Analysis of Chemical Composition of the Essential Oil from Radix Aucklandiae by GC-MS and the Effect on Platelet Aggregation
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Analysis of Chemical Composition of the Essential Oil from Radix Aucklandiae by GC-MS and the Effect on Platelet Aggregation
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 7, Pages: 26-30(2008)
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Published:2008
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HOU Peng-fei1, CHEN Wen-xing1, ZHAO Xin-hui1, et al. Analysis of Chemical Composition of the Essential Oil from Radix Aucklandiae by GC-MS and the Effect on Platelet Aggregation[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(7): 26-30.
DOI:
HOU Peng-fei1, CHEN Wen-xing1, ZHAO Xin-hui1, et al. Analysis of Chemical Composition of the Essential Oil from Radix Aucklandiae by GC-MS and the Effect on Platelet Aggregation[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(7): 26-30.DOI:
Analysis of Chemical Composition of the Essential Oil from Radix Aucklandiae by GC-MS and the Effect on Platelet Aggregation
Objective:To analyze the chemical composition of the essential oil of Radix Aucklandiae and investigate it's influence on platelet aggregation induced by ADP.Methods:The essential oil was extracted from Radix Aucklandiae by steam distillation
and then an analysis was conducted by applying GC-MS(capillary gas chromatography-mass spectrometer)
and investigated for the inhibitory effects on rabbit platelet aggregation in vitro.Results:The experiments showed that 59 components were identified
accounting for 72.91 percent of the total essential oil.The essential oil was mainly composed of dehydrocostuslactone、costunolide、cedrenol、α-elemene、1
7-methyl-etc.Among them Lactones like Dehydrocostuslactone and costunolide are essential components.Conclusions:Fifty nine components were identified in essential oil of Radix Aucklandiae by GC-MS.Volatile oil of Radix Aucklandiae dehydrocostuslactone and costunolide have obvious inhibiting effect on platelet aggregation induced by ADP.The bioactive components derived from terpenes and lanctones in oil of Radix Aucklandiae.
Determination of Costunolide and Dehydrocostuslactone in Baolong Pill by HPLC
Extraction of Effective Compounds from with Microwave-assisted Extraction
Optimization of Cutting Technology Associated with Pharmacodynamic Index for Aucklandiae Radix by Orthogonal Design
GC-MS Analysis on Volatile Components of Wild Trogopterus Feces from Shanyang County of Shaanxi Province
Related Author
LI Hui1
CHEN Bao-tian1
LIU Li2
LIU Qiang2
LIU Jun-hong
LI Di-hua
WU Xiao-xian
ZHANG Xu
Related Institution
Hunan Hansen Pharmaceutical Co.,Ltd
Tianjin Nankai Hospital
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
Henan Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yuyao,Henan Research Center for Special Processing Technology of Chinese Medicine,Henan University of Chinese Medicine
Jiangxi Jingde Chinese Traditional Medicine Co. Ltd.