Effect of Sanyangyixinkang Capsule on Acute Myocardial Ischemia in Dogs
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Effect of Sanyangyixinkang Capsule on Acute Myocardial Ischemia in Dogs
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 10, Pages: 47-49(2008)
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Published:2008
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LI Wei, FU Ping, CHEN Ying-li, et al. Effect of Sanyangyixinkang Capsule on Acute Myocardial Ischemia in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(10): 47-49.
DOI:
LI Wei, FU Ping, CHEN Ying-li, et al. Effect of Sanyangyixinkang Capsule on Acute Myocardial Ischemia in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(10): 47-49.DOI:
Effect of Sanyangyixinkang Capsule on Acute Myocardial Ischemia in Dogs
Objective:To investigate the effect of Sanyangyixinkang Capsule on acute myocardial ischemia in dog.Methods:Acute myocardial infarction model in dog was established by ligating anterior descending coronary artery
using epicardial electrogram mapping to monitor the level of myocardial ischemia
using NBT histochemical stain to determine myocardial infarction size;using biochemical methods to determine AST
CPK
LDH;and using electron microscopy method to observe the morphologic changes of myocardial ischemia.Results:The drug can significantly reduce ∑-ST
N-ST
MIS
and serum AST and CPK levels.Conclusion:The drug has marked improvement and protection for acute myocardial ischemia in dog.