Composition and Biological Activity of Volatile Oil from  Palibin

DENG Ming-qiang1; 2; ZHANG Xiao-ping1; WANG Qiong1; YU Hong1; JIANG Ji-hong3

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Composition and Biological Activity of Volatile Oil from Palibin

更新时间：2024-01-04

- Composition and Biological Activity of Volatile Oil from Palibin
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 14, Issue 2, Pages: 6-8(2008)
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- Published：2008
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DENG Ming-qiang1, 2, ZHANG Xiao-ping1, et al. Composition and Biological Activity of Volatile Oil from Palibin[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(2): 6-8.
DOI：

DENG Ming-qiang1, 2, ZHANG Xiao-ping1, et al. Composition and Biological Activity of Volatile Oil from Palibin[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(2): 6-8. DOI：

摘要

目的:首次从粉背薯蓣的块状茎中提取出挥发油

以检测其生物活性。方法:采用水蒸汽蒸馏法从粉背薯蓣的块状茎中提取出挥发油

再用气相色谱-质谱法对粉背薯蓣的挥发性成分进行研究

并检测其抗肿瘤和抗菌生物活性。结果:从挥发油中分离出7种物质

其中主要成分有对二甲苯(7.601%)

邻苯二甲酸二异丁酯(31.348%)

联苯二甲酸丁醇辛醇酯(1.712%)

正十六烷酸(4.618%)

邻苯二甲酸二丁酯(5.891%)

4-双(1-甲基-1-苯乙基)苯酚(3.471%)

单(2-乙己基)邻苯二甲酸酯(43.875%)

并对挥发油的抗肿瘤活性和抑菌活性进行了检测

发现其化学成分具有较好的抗肿瘤活性和抑菌活性。结论:首次从挥发油的角度来研究粉背薯蓣的药理作用。

Abstract

Objective:The volatile oil was extracted from the stem of Dioscorea hypoglauca Palibin firstly and the biological Activity was tested.Methods: Extract volatile oil from the stem of Dioscorea hypoglauca Palibin by steam distillation and the chemical constituents were analyzed by GC-MS method.The anti-tumor and antibacterial activities of the volatile oil were tested.Results: Seven constituents were identified.The main compounds include p-Xylene(7.601%)

2-Benzened-icarboxylic acid

bis(2-methylpropyl) ester(31.348%)

2Benzenedicarbocylic acid

butyl octyl ester(1.712%)

n-Hexadecanoic acid(4.618%)

Dibutyl phthalate(5.891%)

Phenol

4-bis(1-methyl-1-phenylethyl)-(3.471%)

2-Benzenedicarboxylic acid

mono(2-ethylhexyl) ester(43.875%).We found that the chemical components had activities of anti-tumor and anti-bacterial.Conclusion:The pharmacological effect of Dioscorea hypoglauca Palibin were related with volatile oil.

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Related Author

YE Hong-cui1

LIU Li

LIU Qiang

LIU Nu-yun

XU Li-ying1

ZHANG Xiao-ping2

JIANG Ji-hong2

ZHAO Peng

Related Institution

Inner Mongolia Medical University

School of Basic Medicine， Chengdu University of Traditional Chinese Medicine

Key Laboratory of Modern Preparation of Traditional Chinese Medicine of Ministry of Education， Jiangxi University of Chinese Medicine

Key Laboratory of Natural Medicine Pharmacology of Yunnan Province， School of Pharmacy， Kunming Medical University

State Key Laboratory of Southwestern Chinese Medicine Resources， Chengdu University of Traditional Chinese Medicine

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