Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat
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Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 11, Pages: 44-46(2007)
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Published:2007
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CHE Yan-zhong1, CHEN Hong-bao1, AN Li-feng2, et al. Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 44-46.
DOI:
CHE Yan-zhong1, CHEN Hong-bao1, AN Li-feng2, et al. Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 44-46.DOI:
Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat
Objective:To investigate the effect of Jichuanjian on gastrointestinal peristalsis of senile rats and study relevant mechanism.Methods:The effect of Jichuanjian on gastrointestinal peristalsis of senile rats was observed by small intestine charcoal powder propelling test.The levels of motilin
substance P and somatostain in small intestine of rats were determinated by radioimmunoassay.Results:Different dosage of Jichuanjian can improve gastrointestinal peristalasis of senile rats and increase the levels of motilin
substance P
with reduce the content of somatostatin in small intestine of senile rats significantly.Conclusions:Jichuanjian can enhance the function of gastrointestinal peristalsis of senile rats by a mechanism of promoting secretion of motilin
substance P and lowering the level of somatostatin in intestine.
Effect and Relevant Mechanism of Jichuanjian on Gastrointestinal Peristalsis in Senile Rat
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