Study on Constituents and Biological Activity of Volatile Oil From Tubers of  Hua

YU Hong1; 2; ZHANG Xiao-ping1; DENG Ming-qiang1; YE Hong-cui1; JIANG Ji-hong3

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Study on Constituents and Biological Activity of Volatile Oil From Tubers of Hua

更新时间：2024-01-04

- Study on Constituents and Biological Activity of Volatile Oil From Tubers of Hua
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 14, Issue 5, Pages: 4-5(2008)
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- Published：2008
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YU Hong1, 2, ZHANG Xiao-ping1, et al. Study on Constituents and Biological Activity of Volatile Oil From Tubers of Hua[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 4-5.
DOI：

YU Hong1, 2, ZHANG Xiao-ping1, et al. Study on Constituents and Biological Activity of Volatile Oil From Tubers of Hua[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 4-5. DOI：

摘要

目的:分析多花黄精根状茎挥发油成分及检测其抑菌和抗肿瘤生物活性。方法:采用水蒸汽蒸馏法(SD)提取挥发油

用气相色谱-质谱(GC-MS)联用技术分析多花黄精根状茎精油的成分

生物活性检测采用杯碟法和Alamarblue法。结果:共鉴定出16个化合物

占总挥发油的95.97%

该挥发油对大肠杆菌、金黄色葡萄球菌、红酵母均有较强的抑制能力;对人肺癌细胞(NCI-H460)有显著的抑制作用

当浓度达到100μg·mL-1

抑制率达到98.08%。结论:实验结果表明多花黄精挥发油成分具有较强的生物活性

为进一步研究其药理作用提供了科学依据。

Abstract

Objective:To analyse the constituents and determine the biological activity of volatile oil from the tubers of Polygonatum cyrtonema.Methods:The volatile oil was obtained by steam distillation.And its chemical constituents were analyzed by GC-MS.Biological activity of the volatile oil was screened with microbiological method and Alamar Blue method.Results:16 compounds were identified

making up 95.97% of the total contents;The volatile oil could inhibit the growth of Escherichia coli、Staphylococcus aureus and Rhodotorula glutinis The volatile oil could obviously inhibit the growth of cultured tumor cells

and the inhibitory rate was 98.08% at the volatile oil concentration of 100 μg·mL-1.Conclusion:The results indicated that the biological activity of volatile oil of Polygonatu cyrtonema was strong

and it provided the scientific basis for further develop ment of Polygonatum cyrtonema.

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Related Author

WANG Qiong1

XU Li-ying1

ZHANG Xiao-ping2

JIANG Ji-hong2

ZHAO Peng

ZHANG Man

MU Dan

BAI Wenming

Related Institution

Inner Mongolia Medical University

State Key Laboratory of Southwestern Chinese Medicine Resources， Chengdu University of Traditional Chinese Medicine

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College of Pharmacy， Heilongjiang University of Chinese Medicine

Hubei Research Center of Chinese Materia Medica Processing Engineering and Technology， School of Pharmacy，Hubei University of Chinese Medicine

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