Comparative Study of Zengye Decoction and Sini Decoction in Inhibiting Ventricular Remodeling
|更新时间:2024-01-04
|
Comparative Study of Zengye Decoction and Sini Decoction in Inhibiting Ventricular Remodeling
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 5, Pages: 58-62(2008)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2008
稿件说明:
移动端阅览
WANG Ying, CHEN Chang-xun, DU Jun, et al. Comparative Study of Zengye Decoction and Sini Decoction in Inhibiting Ventricular Remodeling[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 58-62.
DOI:
WANG Ying, CHEN Chang-xun, DU Jun, et al. Comparative Study of Zengye Decoction and Sini Decoction in Inhibiting Ventricular Remodeling[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(5): 58-62.DOI:
Comparative Study of Zengye Decoction and Sini Decoction in Inhibiting Ventricular Remodeling
Objective:To investigate the influence of Zengye Decoction and Sini Decoction on ventricle remodeling.Methods:Ventricular remodeling models were induced by injection of isoproterenol in mice and constriction of abdominal aorta in rats.The effects of Zengye Decoction and Sini Decoction on the heart weight index
blood pressure
AngⅡ
ALD
ET and Hyp levels were assessed.Results:Compared with those of the normal or sham operated group
the heart weight index
blood pressure
the levels of AngⅡ
ET
Hyp in the myocardium and ALD in the blood serum were significantly increased in the model group.In group treated with Zengye Decoction
the heart weight index
blood pressure
the levels of AngⅡ
ET
Hyp in the myocardium and the serum level of ALD were decreased remarkably.Sini Decoction did not show such effects
except that it could decline the level of ET.Conclusions:Zengye Decoction has the effects on inhibiting ventricular remodeling.The mechanism may be related to decreasing the blood pressure and inhibiting neuroendocrine factors.Sini Decoction has no effects on inhibiting ventricular remodeling.
Effect of Linggui Zhugantang on Ventricular Remodeling After Myocardial Infarction and RhoA/ROCK Signaling Pathway
Effect of Qingxin Jieyu Granules Regulating Mitophagy on Ventricular Remodeling After Myocardial Infarction of C57B/L6 Mice
Effect of Bushen Huoxue Prescription on Ventricular Remodeling and Expression of AVP and AQPs in Heart and Brain of Rat Model of Heart Failure after Myocardial Infarction
Influence Mechanism of Myocardial Fibrosis and Vascular Regeneration of Shexiang Tongxin Pills to Syndrome of Qi Deficiency and Blood Stasis in Ischemic Heart Failure
Influence of Tiaopi Huxin Decoction on Ventricular Remodeling and Prognosis of Chronic Heart Failure Based on Theory of Heart Spleen Correlation
Related Author
REN Han
ZHAO Wanzhu
WANG Shushu
CAI Rui
ZHANG Yuanhong
HUANG Shengyi
HUANG Jinling
CHEN Yifan
Related Institution
Anhui Province Key Laboratory of Chinese Medicinal Formula
School of Chinese Medicine,Anhui University of Chinese Medicine
School of Integrated Chinese Medicine and Western Medicine,Anhui University of Chinese Medicine
Research Institute of Integrated Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine
Xiyuan Hospital, China Academy of Chinese Medical Sciences