Effect of Panaxadiol Saponins on NO,NOS Level in Serum in Acute Myocardial Infarction Dogs
|更新时间:2024-01-04
|
Effect of Panaxadiol Saponins on NO,NOS Level in Serum in Acute Myocardial Infarction Dogs
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 4, Pages: 46-49(2008)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2008
稿件说明:
移动端阅览
Liu Jie, LIU Fen, WANG Qiu-jing, et al. Effect of Panaxadiol Saponins on NO,NOS Level in Serum in Acute Myocardial Infarction Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(4): 46-49.
DOI:
Liu Jie, LIU Fen, WANG Qiu-jing, et al. Effect of Panaxadiol Saponins on NO,NOS Level in Serum in Acute Myocardial Infarction Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(4): 46-49.DOI:
Effect of Panaxadiol Saponins on NO,NOS Level in Serum in Acute Myocardial Infarction Dogs
Objective:To investigate the effects of Panaxadiol Saponins(PDS) on the nitric oxide(NO) and nitric oxide synthase(NOS) in serum in acute myocardial infarction(AMI) dogs.Methods:An AMI model was made by ligating left coronary artery in dogs.The content of NO and activity of NOS in serum were detected by spectrophotometric method.N-BT staining method was used to delermin the extent of myocardial infarction and the change in myocardial ultrastructure was observed by transmission electron microscope.Results: Compared with model group
PDS increase the content of NO and activity of NOS in serum.and decrease the extent of myocardial infarction significantly.PDS can alleviate the change induced by ischemia in myocardial ultrastructure markedly.Conclusions: PDS has apparently protective effects on myocardium in acute myocardial infarction dogs.Its mechanisms probably liein increasing NO and NOS level in serum.
Effects of Shuanggen Qinnao Granules on Animal Behavior and Superoxide Dismutase, Malondialdehyde,Nitric Oxide and Nitric Oxide Synthase in Serum of the Rat Model of Vascular Dementia
Effect of Tangzhipiing Granules on Nitric Oxide, Nitric Oxide Synthase and Morphological Changes in Kidney in Rats with Diabetic Nenopathy
Effect of Qingong Capsule on Estrogen in Blood, Content of Nitric Oxide and Activity of Nitric Oxide Synthase in Uterus Homogenate of Rats after Medicine Induced Abortion
Protection Effect of Essential Oil from Rhizome on ox-LDL-induced HAECs Injury via NOS Signal
Effect of Xiongzhi Shigao Tang on Plasma NO, NOS, CGRP and 5-HT, 5-HIAA of Brain in Migraine Model Rats
Related Author
LI Hui
WU Hao-xin
YUE Xiao-jie
ZHENG Hong-yan
LI Chang-xin
XIE Dong-xia
HUANG Xian-zhang
LI Hui
Related Institution
Anhui Province Key Laboratory of Chinese Medicinal Formula
School of Chinese Medicine,Anhui University of Chinese Medicine
School of Integrated Chinese Medicine and Western Medicine,Anhui University of Chinese Medicine
Henan University of Chinese Medicine
School of Basic Medicine and Forensic Medicine,Henan University of Science and Technology