The Effect of Xue Fu Zhu Yu Granule on Cardial Oxygen Metabolism and Myocardial Infarction EECG in Dogs
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The Effect of Xue Fu Zhu Yu Granule on Cardial Oxygen Metabolism and Myocardial Infarction EECG in Dogs
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 11, Pages: 24-26(2007)
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Published:2007
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WANG Qiu-jin1, LIU Jie1, LIU Fen1, et al. The Effect of Xue Fu Zhu Yu Granule on Cardial Oxygen Metabolism and Myocardial Infarction EECG in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 24-26.
DOI:
WANG Qiu-jin1, LIU Jie1, LIU Fen1, et al. The Effect of Xue Fu Zhu Yu Granule on Cardial Oxygen Metabolism and Myocardial Infarction EECG in Dogs[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 24-26.DOI:
The Effect of Xue Fu Zhu Yu Granule on Cardial Oxygen Metabolism and Myocardial Infarction EECG in Dogs
Objective:To observe the effects of Xue Fu Zhu Yu Granule(XFZHYG) on cardial oxygen metabolism and its influmce on acute myocardial infarction EECG in anesthetic dogs.Methods:Twenty-four dogs were devided randomly in four groups: normal conrol group
positive control group
2.5 g·kg-1 XFZHYG group;5.0 g·kg-1 XFZHYG group.The cardial oxygen metabolism parameters were measured in the anaesthetiz dogs.The degree and range of myocardial ischemia
were determined by using the acute myocardial infarction model of ligation of left anterior descending(LAD) in the anaesthetized open-chest dogs.Results:Compared with normal control group
the cardial oxygen consumption decreased in 2.5 g·kg-1 XFZHYG group and 5.0 g·kg-1 XFZHYG group
the degree and range of myocardial ischemia also decreased.XFZHYG has protective effects on myocardial ischemia in dogs.Conclusion:XFZHYG can decrease cardial oxygen consumption in dogs.XFZHYG has protective effects on myocardial ischemia in dogs.