The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats
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The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 11, Pages: 34-36(2007)
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Published:2007
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REN Jian-xun, LIN Cheng-ren, Wang Min, et al. The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 34-36.
DOI:
REN Jian-xun, LIN Cheng-ren, Wang Min, et al. The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(11): 34-36.DOI:
The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats
Objective:To study the effect and mechanism of Niuhuang Jiangya Capsule on the function of platelet in rats.Methods:Healthy SD rats were fed with Niuhuang Jiangya Capsule(0.3
0.15
0.075 g·kg-1)for 7days;then the platelet adhension rates and the ADP-induced platelet agglutinate rate as well as the contents of CaM and TXA2 in platelets were measured.Results:Niuhuang Jiangya Capsule could reduce the platelet adhension rate and the ADP-induced platelete agglutinate rate
as well as the contents of CaM and TXA2 in platelets.Conculsion:Niuhuang Jiangya Capsule can suppress platelet agglutinate and adhension by interventing different pathways of platelet activation.
The Effect and Mechanism of Niuhuang Jiangya Capsule on the Function of Platelets in Rats
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Related Author
REN Jian-xun
LIN Cheng-ren
WANG Min
XU Hui
LIU Jian-xun~
DOU Xin
PAN Haidi
HE Changhui
Related Institution
Xi Yuan Hospital,China Academy of Chinese Medicinal Sciences
中国中医科学院西苑医院基础研究室 北京100091
The First Clinical Medical College,Shandong University of Traditional Chinese Medicine(TCM)
College of TCM,Shandong University of TCM
The Affiliated Hospital of Shandong University of TCM