Therapeutic Effect of JiuGanQing Capsule on Experimetal Alcoholic Fatty Liver in Rats
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Therapeutic Effect of JiuGanQing Capsule on Experimetal Alcoholic Fatty Liver in Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 14, Issue 3, Pages: 53-55(2008)
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Published:2008
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DI Lin1, LIU Xin-yu1, JIN Xiang-qun2, et al. Therapeutic Effect of JiuGanQing Capsule on Experimetal Alcoholic Fatty Liver in Rats[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(3): 53-55.
DOI:
DI Lin1, LIU Xin-yu1, JIN Xiang-qun2, et al. Therapeutic Effect of JiuGanQing Capsule on Experimetal Alcoholic Fatty Liver in Rats[J]. Chinese journal of experimental traditional medical formulae, 2008, 14(3): 53-55.DOI:
Therapeutic Effect of JiuGanQing Capsule on Experimetal Alcoholic Fatty Liver in Rats
Objective:To investigate the effect of Jiuganqing capsule on alcoholic fatty liver.Methods:Alcoholic fatty liver of Wister rat was in duced by ig 56° alcohol liquid 5 mL·kg-1 twice a day for 4 week.The model is determined by histopathologic examination.The model group was given alcohol liquid as mentioned above.The masculine drug group was given Gypenosides ig 25 mg·kg-1 daily and alcohol as the model.Jiuganqing capsule high
middle and low dose-group was separately give ig 0.6
0.3
0.15 g·kg-1 and alcohol as the modes for 4 week.The content of ALT
AST
TG
T-CHO
SOD
MDA
TP
Alb and TNF-a in serum were detected.The hepatic index was calculated by weighing liver.The activity of TG
TC
MDA
ALT
AST and SOD in hepatic hemogenate were detected.Results:Jiuganqing capsule can obviously reduce activity of ALT
AST and the content of T-CHO、TG、MDA
TNF-α but increase the content of Alb and activity of SOD.Conclusion:Jiuganqing capsule has obviously therapeutic effect on alcoholic fatty liver in rat.
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Related Institution
School of Basic Medicine, Gansu University of Chinese Medicine
Gansu Key Laboratory of Traditional Chinese Medicine Formula Innovation and Transformation
Key Laboratory of Dunhuang Medicine, Ministry of Education, Gansu University of Chinese Medicine
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