Influences of Divided Formula for Resolving Phlegm and Promoting Blood Circulation on the Expression of Scavenger Receptor,Class B Type Ⅰ(SR-BⅠ) in the Liver of the Hyperlipemia-modeled Rats
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Influences of Divided Formula for Resolving Phlegm and Promoting Blood Circulation on the Expression of Scavenger Receptor,Class B Type Ⅰ(SR-BⅠ) in the Liver of the Hyperlipemia-modeled Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 7, Pages: 35-37(2007)
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Published:2007
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WEN Li1, LIU Song-lin1, YE Yong2, et al. Influences of Divided Formula for Resolving Phlegm and Promoting Blood Circulation on the Expression of Scavenger Receptor,Class B Type Ⅰ(SR-BⅠ) in the Liver of the Hyperlipemia-modeled Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(7): 35-37.
DOI:
WEN Li1, LIU Song-lin1, YE Yong2, et al. Influences of Divided Formula for Resolving Phlegm and Promoting Blood Circulation on the Expression of Scavenger Receptor,Class B Type Ⅰ(SR-BⅠ) in the Liver of the Hyperlipemia-modeled Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(7): 35-37.DOI:
Influences of Divided Formula for Resolving Phlegm and Promoting Blood Circulation on the Expression of Scavenger Receptor,Class B Type Ⅰ(SR-BⅠ) in the Liver of the Hyperlipemia-modeled Rats
Objective:To observe the influences divided formula for resolving phlegm and promoting blood circulation on the expression of scavenger receptor
class B type Ⅰ(SR-BⅠ) in the liver of the hyperlipemia-modeled rats.Methods:50 Wistar rats were divided randomly into 5 groups:blank group
model group
full formula group
group of taking drugs for resolving phlegm
and group of taking drugs for promoting blood circulation.The model was established by high fat feeding into stomach daily except the blank group.After 30 days RT-PCR was adopted to messure the level of SR-BⅠ mRNA for each group.Results:The level of SR-BⅠ mRNA of model group was apparently lower than that of blank group.Compared to that of the model
SR-BⅠ mRNA of the full formula group and the group of taking drugs for resolving phlegm increased evidently
but there was no difference between model group and the group of taking drugs for promoting blood circulation for SR-BⅠ mRNA.Conclusion:In the full formula
the drugs for resolving phlegm play the most important role in elevating the level of SR-BⅠ mRNA in the liver of the hyperlipemia-modeled rats.
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