Effect of Tatal Saponins of Ophiopogon on Experimental Hyperglycemias Mice

GAO Chang-kun1; GAO Jian1; XU Xian-xiang2

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Effect of Tatal Saponins of Ophiopogon on Experimental Hyperglycemias Mice

更新时间：2024-01-04

- Effect of Tatal Saponins of Ophiopogon on Experimental Hyperglycemias Mice
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 13, Issue 5, Pages: 33-34(2007)
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- Published：2007
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GAO Chang-kun1, GAO Jian1, XU Xian-xiang2. Effect of Tatal Saponins of Ophiopogon on Experimental Hyperglycemias Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(5): 33-34.
DOI：

GAO Chang-kun1, GAO Jian1, XU Xian-xiang2. Effect of Tatal Saponins of Ophiopogon on Experimental Hyperglycemias Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(5): 33-34. DOI：

摘要

目的:研究麦冬总皂苷对实验性糖尿病小鼠血糖的影响。方法:麦冬总皂苷(100

200

400mg/kg)灌胃

测定正常小鼠及由四氧嘧啶、肾上腺素、葡萄糖所致高血糖小鼠血糖水平。结果:麦冬总皂苷对四氧嘧啶、肾上腺素及葡萄糖引起的小鼠高血糖均有抑制作用。结论:麦冬总皂苷对实验性高血糖小鼠有明显的降糖作用。

Abstract

Objective:To study the effect of total saponins of Ophiopogon on blood sugar in experimental diabetic mice.Methods:Mice were raised with total saponins of Ophiopogan(100

200

400 mg/kg).The levels of blood sugar were calculated in experimental hyperglycemias induced by alloxan(100 mg/kg)

adrenaline(0.02 mg/kg) and glucose(2 g/kg).Results:Total saponins of ophiopogan was found to decrease various experimental hyperglycemias induced by alloxam

adrenaline and glucose.Conclusion:Total saponins of Ophiopogon has significant hypoglycemic effect on the experimental hyperglycemias in mice.

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