Study on Material Basis and Mechanism of Action of Dangguishaoyaosan in the Prevention and Treatment of Senile Dementia Ⅸ:The Anti-oxidative Activity of The Polysaccharides of FBD
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Study on Material Basis and Mechanism of Action of Dangguishaoyaosan in the Prevention and Treatment of Senile Dementia Ⅸ:The Anti-oxidative Activity of The Polysaccharides of FBD
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 7, Pages: 23-25(2007)
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Published:2007
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WU Feng, ZHU Dan-ni, LIN Zhi-hong, et al. Study on Material Basis and Mechanism of Action of Dangguishaoyaosan in the Prevention and Treatment of Senile Dementia Ⅸ:The Anti-oxidative Activity of The Polysaccharides of FBD[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(7): 23-25.
DOI:
WU Feng, ZHU Dan-ni, LIN Zhi-hong, et al. Study on Material Basis and Mechanism of Action of Dangguishaoyaosan in the Prevention and Treatment of Senile Dementia Ⅸ:The Anti-oxidative Activity of The Polysaccharides of FBD[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(7): 23-25.DOI:
Study on Material Basis and Mechanism of Action of Dangguishaoyaosan in the Prevention and Treatment of Senile Dementia Ⅸ:The Anti-oxidative Activity of The Polysaccharides of FBD
Objective:To observe the anti-oxidative activity of the polysaccharides(P1) of FBD.Methods:The oxidative injured model of PC12 and ECV304 cells induced by H2O2 were used to measure the oxidation prevention of FBD Ps on cells which was observed with MTT metherd.The oxidative injured model of mice induced by cyclophosphamide was used
the activities of SOD and MDA in brains were measured.Results:The FBD Ps has noteable functions of oxidation prevention on the oxidative injured model of PC12 and ECV304 cells in concentrations of 200 mg/kg and 400 mg/kg FBD Ps.They also can rise the activity of SOD and decline the content of MDA.Conclusions:FBD Ps has notable function for oxidation prevention.This maybe the basis of its function for VD prevention.