Influence of Zuoguiyin on Antioxiadation in Blood Thymus and Spleen Index of Senile Mice

WANG Yan; ZHAO Yi

您当前的位置：

首页 >

文章列表页 >

Influence of Zuoguiyin on Antioxiadation in Blood Thymus and Spleen Index of Senile Mice

更新时间：2024-01-04

- Influence of Zuoguiyin on Antioxiadation in Blood Thymus and Spleen Index of Senile Mice
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 13, Issue 3, Pages: 67-69(2007)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2007
- 稿件说明：
移动端阅览
WANG Yan, ZHAO Yi. Influence of Zuoguiyin on Antioxiadation in Blood Thymus and Spleen Index of Senile Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(3): 67-69.
DOI：

WANG Yan, ZHAO Yi. Influence of Zuoguiyin on Antioxiadation in Blood Thymus and Spleen Index of Senile Mice[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(3): 67-69. DOI：

摘要

目的:从抗氧化作用及免疫器官指数角度探讨左归饮延缓衰老的作用机理。方法:以5.5 g/(kg·d)浓缩左归饮煎液自由饮75 d

并以老年小鼠作对照

观察左归饮对老年小鼠血清丙二醛(MDA)、超氧化物歧化酶(SOD)、总抗氧化能力(T-AOC)及胸腺指数、脾指数的影响。结果:老年小鼠与青年小鼠比较MDA含量明显升高

SOD活性、T-AOC、胸腺指数和脾指数显著降低。应用左归饮则使老年小鼠上述指标明显恢复

且差异显著。结论:左归饮能增强老年小鼠的抗氧化能力

减少自由基对细胞膜的损伤

抑制免疫器官的退化和萎缩

起到延缓衰老的作用。

Abstract

Objective:To explore the free radical mechanism of Zuoguiyin(ZGY) in delaying senility.Methods:After the ZGY group of mice had freely drunk the concentrated decoction for 75 days

and compared with the old control group

we observed the effect on the indices of thymus index

spleen index

the contents of MDA

the activities of SOD and T-AOC of serum.Results:Compared to the young control group

the old control group showed significant increase in the contents of MDA in blood

significant decrease in the activities of SOD

T-AOC in blood

and decrease in thymus index and spleen index.The ZGY group showed significant improvement for the above parameters compared with the old control group.The differences were statistically significant.Conclusion:Zuoguiyin could delay the senility

which might be related with increasing antioxdation and thymus index and spleen index

meanwhile

reducing the damage of free radical to cell membrane.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Inhibitory Effect of LAMS Against Prostatic Cancer in Tumor-earing Mice

Historical Evolution and Key Information Research on Famous Classical Formula Zuoguiyin

Experimental Study on Complemental Antitumor Effect of Fuzheng Kangliu Decoction

Protective Effect of Total Flavonoids of Bidens on Acute Liver Injury Induced by -GalN in Mice

Related Author

CUI Fei-lun

SHENG Yu-qing

ZOU Ming-chang

LIU Tao

WEI Kaifeng

SHI Yangkai

SUN Xiaoxia

JI Xun

Related Institution

School of Chinese Medicine，Nanjing University of Chinese Medicine

Nanyang College of Technology

College of TCM,Southern Medical University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰