Objective:To study the effect of Xuekang Koufuye on mice models of idiopathic thrombocytopenic purpura(ITP).Methods:Guinea pig anti-mice platelet serum(GP-APS) was diluted with saline(1∶4)

and intravitreal injected(5 mL/kg) into mice once in 2 days for 15 days.Two dosage of Xuekang Koufuye was given orally to mice in 15 days since mice models of ITP were established.Results:Xuekang Koufuye can enhance the amount of platelets

promote the mature of megakaryocyte of mice significantly and improve the histological pathology of spleen.Conclusions:Xuekang Koufuye is an effective and safety medicine in treating ITP

and can be used widely in clinic.