Study on Antipyretic Effect and Its Mechanism of Cinnamaldehyde
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Study on Antipyretic Effect and Its Mechanism of Cinnamaldehyde
Chinese Journal of Experimental Traditional Medical FormulaeVol. 13, Issue 4, Pages: 22-25(2007)
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Published:2007
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MA Yue-ying1, LI Cang-hai2, GUO Jian-you1, et al. Study on Antipyretic Effect and Its Mechanism of Cinnamaldehyde[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 22-25.
DOI:
MA Yue-ying1, LI Cang-hai2, GUO Jian-you1, et al. Study on Antipyretic Effect and Its Mechanism of Cinnamaldehyde[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(4): 22-25.DOI:
Study on Antipyretic Effect and Its Mechanism of Cinnamaldehyde
Objective:To investigate the antipyretic effect and its mechanism of cinnamaldehyde.Methods:The rat febrile models induced by injecting fresh yeast subcutaneously and the mouse cerebral microvascular endothelial cells(bEnd.3) stimulated by IL-1β were adopted in the experiment.The contents of PGE2 in the hypothalamus and in conditioned media of bEnd.3 stimulated by IL-1β were measured by ELISA
respectively.Results:Cinnamaldehvde showed marked antipyretic effect on the yeast-induced fever
and remarkable decreased the contents of PGE2 in the hypothalamus of febrile rats and in the conditioned media of bEnd.3 induced by IL-1β.Conclusions:Cinnamaldehyde has obvious antipyretic effect
which might be related with the interferencing the content of PGE2.
Inhibitory Effect of Cinnamaldehyde on Proliferation, Migration and Tube Formation of VEGF-induced Endothelial Cells via JAK2/STAT3 Pathway
Effect and Mechanism of Active Fraction A of Guizhi Decoctionon(桂枝汤) on Dual-directional Thermoregulation——Effect on Prostaglandin E in Hypothalamus of Rats
Determination of Hesperidin and Cinnamaldehyde in Hewei Powder by HPLC
Effects of Guizhitang and It’s Biotransformation Product on Catabolizing Enzymes of Prostaglandin Ein bEnd.3 with Interleukin- 1 β Inducement
Anti-inflammatory and Analgesic Effects of Extracts from the Leaves of
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Related Institution
Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing Key Laboratory of Pharmacology of Chinese Materia Medica
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