Objective:To study the inducing effect of Jianpi Bushen Formulation(JPBS) on apoptosis and the level of mitochondrial membrane potential(MMP) in 615 murine with MFC after surgical operation.Methods:615 murine with MFC after surgical operation was adopted as animal model.JPBS were orally delivered to the animals for therapy.The effects were evaluated by inhibition of local recurrence tumor.Apoptosis and the level of MMP of those was detected respectively using flow cytometry(FCM).Results:After treatment

the weight of recurrence tumor of JPBS group was obviously lower than that of model group.The inhibition rate of recurrence tumor of JPBS group was 71.07%.Apoptotic index of JPBS group was obviously higher than that of model group.The MMP level of JPBS group was obviously lower than that of model group.(all P<0.01) Conclusions:JPBS were effective for local recurrence tumor after resection of primary tumor.The MMP level of local recurrence tumor may be degraded

and apoptosis of that my be induced by JPBS.