Pharmacodynamic Effects of Manjieling Capsule on Ulcerative Colitis in Rat
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Pharmacodynamic Effects of Manjieling Capsule on Ulcerative Colitis in Rat
Chinese Journal of Experimental Traditional Medical FormulaeVol. 12, Issue 2, Pages: 46-50(2006)
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Published:2006
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LIU Xin-yu1, DI Lin1, CHEN Xiao-guang1, et al. Pharmacodynamic Effects of Manjieling Capsule on Ulcerative Colitis in Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 46-50.
DOI:
LIU Xin-yu1, DI Lin1, CHEN Xiao-guang1, et al. Pharmacodynamic Effects of Manjieling Capsule on Ulcerative Colitis in Rat[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 46-50.DOI:
Pharmacodynamic Effects of Manjieling Capsule on Ulcerative Colitis in Rat
Objective:To study effects of Manjieling Capsule on ulcerative colitis.Method:The spleen insufficiency
the acute ulcerative colitis and immune ulcerative colitis models of rat were made by oral administration of Folium sennae
aoetic acid and rabbit mucous membrane of intestine protein
respectively.Result:The oral administration of Manjieling Capsule with dosage of 1.16
0.58
0.29g/kg can alleviate the pathological changes in the acute and immune ulcerative colitis and decrease the content of MDA
NO with increased activity of SOD.The decreased of TNF and IgG content
increase of IL-2 and regulation of lymphocyte subgroup proportion were found.Meanwhile
the oral administration of Manjieling Capsule with dosage of 1.16
0.58
0.29g/kg can inhibit swelling of the ears caused by xylene
reduce the blood capillary permeability of the abdominal cavity and twisting reaction with increased pain threshold value in mice.Conclusion:These results indicated that Manjieling Capsule had effects on ulcerative colitis.
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Mechanisms of Zhuyuwan in Treating both Intrahepatic Cholestasis and Ulcerative Colitis Based on Homotherapy for Heteropathy
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Shaoyaotang Restores Th17/Treg Cell Balance by Regulating Glucose Metabolism Reprogramming in Treatment of Ulcerative Colitis
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