Study on the in Vitro Release of Multi-target Ingredients in Compound Danshen Sustained-release Tablets

LI Yuan-xin; YUAN Xu-jiang; ZHU Sheng-shan

您当前的位置：

首页 >

文章列表页 >

Study on the in Vitro Release of Multi-target Ingredients in Compound Danshen Sustained-release Tablets

更新时间：2024-01-04

- Study on the in Vitro Release of Multi-target Ingredients in Compound Danshen Sustained-release Tablets
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 12, Issue 8, Pages: 7-9(2006)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2006
- 稿件说明：
移动端阅览
LI Yuan-xin, YUAN Xu-jiang, ZHU Sheng-shan. Study on the in Vitro Release of Multi-target Ingredients in Compound Danshen Sustained-release Tablets[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(8): 7-9.
DOI：

LI Yuan-xin, YUAN Xu-jiang, ZHU Sheng-shan. Study on the in Vitro Release of Multi-target Ingredients in Compound Danshen Sustained-release Tablets[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(8): 7-9. DOI：

摘要

目的:建立复方丹参缓释片多指标成分的体外释放度测定方法

评价其体外释药行为。方法:采用高效液相色谱法、气质联用法和释放度试验

研究复方丹参缓释片中水溶性、脂溶性、挥发性成分在不同溶出时间的累积释放度。结果:丹酚酸B、人参皂苷Rg1、丹参酮ⅡA、冰片具有相似的释药行为

符合一级、Higuchi方程。结论:本法简便、快速

适用于复方丹参缓释片的体外释放度测定。

Abstract

Objective:To develop the methods to determine the in vitro release of multi-target ingredients in Compound Danshen Sustained-release Tablets and to evaluate its release behavior in vitro.Methods:HPLC

GC-MS and the release test were applied to determine the accumulated release rate of water-soluble

liposoluble and evaporable constituents in Compound Danshen Sustained-release Tablets in different time.Results:Salvianolic acid B

ginsenoside Rg1

tanshinone ⅡA and borneol had a similar release behavior and corresponded first-degree and Higuchi equations.Conclusions:The method is convenient and quick

and can be used for the determination of the in vitro release of multi-target ingredients in Compound Danshen Sustained-release Tablets.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Study on Optimization of Formula of Total Alkaloids of Aconitum Sinomontanum Nakai Sustained-release Tablets

Related Author

HUANG Tao

ZHU Xue-yu

ZHANG Tie-jun

HUANG Tao1

ZHU Xue-yu2

ZHANG Tie-jun2

Related Institution

Tianjin Medical University

Tianjin Institute of Pharmaceutical Research

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰