Chinese Journal of Experimental Traditional Medical FormulaeVol. 12, Issue 7, Pages: 38-41(2006)
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Published:2006
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LI Ji-hong, DAI Dong-mei, LI Min. Pharmacological Effects of Chuanbei Xueli Extract[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 38-41.
DOI:
LI Ji-hong, DAI Dong-mei, LI Min. Pharmacological Effects of Chuanbei Xueli Extract[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 38-41.DOI:
Objective:To investigate the main pharmacological effects of a Chinese traditional compound
Chuanbei Xueli Extract.Methods:The following experiments were carried out:cough induced by ammonia and sulfur dioxide
in vivo and in vitro tests for relieving asthma
phlegm removing with phenol red and capillary
fever caused by dried yeast and triple vaccine
and the inflammation model caused by dimethylbenzene and carrageenin.The effects of the drug on inhibiting cough
relieving asthma
removing phlegm
reducing fever
and antagonizing inflammation were investigated.Results:Chuanbei Xueli Extract significantly prolonged the latent period of cough in mice
increased the latent period of induced asthma in guinea pigs
relaxed the isolated tracheal smooth muscle of guinea pigs
increased the elimination of phenol red in mice
increased the elimination of phlegm volume in rats
lowered the high temperature of rabbits caused by triple vaccine
and inhibited the imflammatorys welling caused by dimethylbenzene and carrageenin.Conclusions:Chuanbei Xueli Extract has significant effects on inhibiting cough