Application of Modern Technology in Heredity Toxicity of Traditional Chinese Drugs

HU Jian-ping1; 2; LIU Chun-fang1; LIN Na1

您当前的位置：

首页 >

文章列表页 >

Application of Modern Technology in Heredity Toxicity of Traditional Chinese Drugs

更新时间：2024-01-04

- Application of Modern Technology in Heredity Toxicity of Traditional Chinese Drugs
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 12, Issue 8, Pages: 66-70(2006)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2006
- 稿件说明：
移动端阅览
HU Jian-ping1, 2, LIU Chun-fang1, et al. Application of Modern Technology in Heredity Toxicity of Traditional Chinese Drugs[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(8): 66-70.
DOI：

HU Jian-ping1, 2, LIU Chun-fang1, et al. Application of Modern Technology in Heredity Toxicity of Traditional Chinese Drugs[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(8): 66-70. DOI：

摘要

以常用的细菌回复突变试验、微核实验、单细胞凝胶电泳等实验方法以及近年来发展成熟的基因芯片技术和胚胎干细胞技术为代表

概要论述了现代实验技术的特点及其在中药遗传毒性研究中的应用现状和优势。细胞回复突变试验、微核实验、单细胞凝胶电泳试验等已成为常规的新药毒理评价实验方法

并广泛应用于中药的毒理研究中。而基因芯片技术和胚胎干细胞技术是近一、二十年发展起来并逐渐成熟的新技术

具有高精度、高通量和低消耗的特点

是其它技术所无法比拟的

尽管目前在中药毒理研究中的应用尚属初步阶段

但随着中药现代化的不断发展

其在中药遗传毒性研究中的地位必将日显突出

发挥越来越重要的作用。

Abstract

Based on Ames test

micronuclei experiment

single cell gel electrophoresis(SCGE)

gene array and embryonic stem cell(ESC) technology

the article summerized the feature of these modern technologies and their application in heredity toxicity of traditional Chinese medicine(TCM).Ames test

micronuclei experiment and SCGE have been used to assess toxicity of new drugs

and widely applied in the research of TCM toxicity.Meanwhile

gene array and ESC technology developed in recent years are incomparable for their high precision

high throughput and low expenditure.Although their application in TCM toxicity is still in initial stage

these modern technologies will become more and more improtant in the research of heredity toxicity of traditional Chinese drugs.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Traditional Chinese Medicine in Treatment of Constipation Based on 5-HT Signaling Pathway： A Review

Related Author

LIANG Yong

GE Bin

SHI Yu

ZHANG Yang

ZHANG Hongxi

Related Institution

Liaoning University of Traditional Chinese Medicine（TCM）

Third Affiliated Hospital of Liaoning University of TCM

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰