Study on Quality Standards for Jiakangling Granules
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Study on Quality Standards for Jiakangling Granules
Chinese Journal of Experimental Traditional Medical FormulaeVol. 12, Issue 6, Pages: 22-24(2006)
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Published:2006
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GAO Shang, ZHAO Di-jia, YI Zhi-heng, et al. Study on Quality Standards for Jiakangling Granules[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(6): 22-24.
DOI:
GAO Shang, ZHAO Di-jia, YI Zhi-heng, et al. Study on Quality Standards for Jiakangling Granules[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(6): 22-24.DOI:
Study on Quality Standards for Jiakangling Granules
Objective:To establish the quality control standards for Jiakangling Granules(Herba ecliptae
Radix salviae miltiorrhizae
Os dragonis etc).Methods:HPLC method was developed for the determination of Salvianolic acid A in Jiakangling Granules.The analysis was carroed on(HYPERSIL#BDS C18 4.6mm×200mm) column eluted with acetonitrile-water-polyphosphoric(2∶53∶0.5) as a mobile phase and detection wavelength at 280 nm.TLC method was developed for the identification of Herba ecliptae.Results:The content of salvianolic acid A was linear at the range of 1.06~6.36μg
average recovery was 97.40% and RSD was 2.1(n=5).TLC spots clear and specific.Conclusion:These methods are accurate and reliable with a smang specificity and can be used for the quality control of Jiakangling Granules.
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Li-ying YU
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Related Institution
Center for Drug Evaluation,National Medical Products Administration
China Academy of Chinese Medical Sciences
Guangxi Engineering Research Center of Traditional Chinese Medicine Resource Intelligent Creation,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants
Food and Drug Department,Ministry of Health
College of Pharmacy, Hunan Provincial Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine(TCM), Laboratory of Supramolecular Mechanism and Mathematic-Physics Chracterization for Chinese Materia Medica, Hunan University of Chinese Medicine