Determination of Total Aristolochic Acid in Traditional Chinese Medicines Containing Aristolochic Acid By Ultraviolet Spectrophotometry
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Determination of Total Aristolochic Acid in Traditional Chinese Medicines Containing Aristolochic Acid By Ultraviolet Spectrophotometry
Chinese Journal of Experimental Traditional Medical FormulaeVol. 12, Issue 2, Pages: 11-13(2006)
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Published:2006
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LI Lin1, WANG Zhi-min1, GAO Hui-min1, et al. Determination of Total Aristolochic Acid in Traditional Chinese Medicines Containing Aristolochic Acid By Ultraviolet Spectrophotometry[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 11-13.
DOI:
LI Lin1, WANG Zhi-min1, GAO Hui-min1, et al. Determination of Total Aristolochic Acid in Traditional Chinese Medicines Containing Aristolochic Acid By Ultraviolet Spectrophotometry[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 11-13.DOI:
Determination of Total Aristolochic Acid in Traditional Chinese Medicines Containing Aristolochic Acid By Ultraviolet Spectrophotometry
Objective:To develop a determination method of total aristolochic acid by ultraviolet spectrophotometry to ensure cliriical safety and therapeutic efficacy.Methods:The samples were analyzed by ultraviolet spectrophotometry and detected at wave length of 390nm.Results:The calibration curve was linear(r=0.9992) within the range of 0.047~0.235mg for aristolochic acid A.The average recovery was 98.16%.RSD=2.04%.Conclusion:The method with good linear relationship was convenient
quick
accurate
and suitable for the quality control of the total aristolochic acid in traditional Chinese medicines containing aristolochic acid.
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