Study of the Anti-atherosclerotic Mechanisms by Dahuang Zhechong Pill
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Study of the Anti-atherosclerotic Mechanisms by Dahuang Zhechong Pill
Chinese Journal of Experimental Traditional Medical FormulaeVol. 12, Issue 5, Pages: 32-34(2006)
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Published:2006
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LI Jing-li, LIU Jun-tian, GOU Wei, et al. Study of the Anti-atherosclerotic Mechanisms by Dahuang Zhechong Pill[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(5): 32-34.
DOI:
LI Jing-li, LIU Jun-tian, GOU Wei, et al. Study of the Anti-atherosclerotic Mechanisms by Dahuang Zhechong Pill[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(5): 32-34.DOI:
Study of the Anti-atherosclerotic Mechanisms by Dahuang Zhechong Pill
Aim:To observe the anti-atherosclerotic mechanisms by Dahuang Zhechong pill.Methods:The atherosclerotic model was established by hypercholesterol feeding together with immune-injured endothelium in rabbits.The levels of blood lipid and MDA in the serum were determined.Histological examination was done by light microscopes.Results:The results showed that the level of MDA was decreased and the level of blood lipid wasn't significantly changed in Dahuang Zhechong pill-administered groups in comparison with the control group.Histological examination showed the reduced area of atherosclerotic plaque in aorta
the lightened intimal hyperplasia
descreased foam cells in drug-administered groups.Conclusions:Dahuang Zhechong pill can inhibit the development of early atherosclerosis by the non-lowering lipid mechanisms